Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM1552C | 0.0033 | uM | 24 | hr | | p-Histone H3(S10) | 226.97 | p-Rb(S807/S811) | 112.19 | p-S6(S235/S236 | 400.08 | 1 | WM1552C-signal2 | B10 | |
| Vemurafenib | WM1552C | 0.0000 | uM | 24 | hr | | p-Histone H3(S10) | 221.69 | p-Rb(S807/S811) | 117.69 | p-S6(S235/S236 | 423.70 | 1 | WM1552C-signal2 | B11 | |
| Vemurafenib | WM1552C | 5.0000 | uM | 24 | hr | | p-Histone H3(S10) | 174.85 | p-Rb(S807/S811) | 52.10 | p-S6(S235/S236 | 261.40 | 1 | WM1552C-signal2 | B2 | |
| Vemurafenib | WM1552C | 2.0000 | uM | 24 | hr | | p-Histone H3(S10) | 123.39 | p-Rb(S807/S811) | 42.15 | p-S6(S235/S236 | 347.41 | 1 | WM1552C-signal2 | B3 | |
| Vemurafenib | WM1552C | 0.8000 | uM | 24 | hr | | p-Histone H3(S10) | 153.80 | p-Rb(S807/S811) | 53.66 | p-S6(S235/S236 | 392.09 | 1 | WM1552C-signal2 | B4 | |
| Vemurafenib | WM1552C | 0.3200 | uM | 24 | hr | | p-Histone H3(S10) | 144.13 | p-Rb(S807/S811) | 66.51 | p-S6(S235/S236 | 373.65 | 1 | WM1552C-signal2 | B5 | |
| Vemurafenib | WM1552C | 0.1280 | uM | 24 | hr | | p-Histone H3(S10) | 208.13 | p-Rb(S807/S811) | 96.36 | p-S6(S235/S236 | 376.62 | 1 | WM1552C-signal2 | B6 | |
| Vemurafenib | WM1552C | 0.0512 | uM | 24 | hr | | p-Histone H3(S10) | 198.26 | p-Rb(S807/S811) | 101.11 | p-S6(S235/S236 | 404.63 | 1 | WM1552C-signal2 | B7 | |
| Vemurafenib | WM1552C | 0.0205 | uM | 24 | hr | | p-Histone H3(S10) | 181.99 | p-Rb(S807/S811) | 102.95 | p-S6(S235/S236 | 423.14 | 1 | WM1552C-signal2 | B8 | |
| Vemurafenib | WM1552C | 0.0082 | uM | 24 | hr | | p-Histone H3(S10) | 217.23 | p-Rb(S807/S811) | 107.32 | p-S6(S235/S236 | 400.59 | 1 | WM1552C-signal2 | B9 | |
| Vemurafenib | WM1552C | 0.0033 | uM | 24 | hr | | p-Histone H3(S10) | 182.24 | p-Rb(S807/S811) | 111.29 | p-S6(S235/S236 | 389.65 | 2 | WM1552C-signal2 | C10 | |
| Vemurafenib | WM1552C | 0.0000 | uM | 24 | hr | | p-Histone H3(S10) | 216.59 | p-Rb(S807/S811) | 117.74 | p-S6(S235/S236 | 410.72 | 2 | WM1552C-signal2 | C11 | |
| Vemurafenib | WM1552C | 5.0000 | uM | 24 | hr | | p-Histone H3(S10) | 184.35 | p-Rb(S807/S811) | 50.13 | p-S6(S235/S236 | 228.77 | 2 | WM1552C-signal2 | C2 | |
| Vemurafenib | WM1552C | 2.0000 | uM | 24 | hr | | p-Histone H3(S10) | 120.64 | p-Rb(S807/S811) | 41.60 | p-S6(S235/S236 | 325.46 | 2 | WM1552C-signal2 | C3 | |
| Vemurafenib | WM1552C | 0.8000 | uM | 24 | hr | | p-Histone H3(S10) | 177.12 | p-Rb(S807/S811) | 56.01 | p-S6(S235/S236 | 356.27 | 2 | WM1552C-signal2 | C4 | |
| Vemurafenib | WM1552C | 0.3200 | uM | 24 | hr | | p-Histone H3(S10) | 167.82 | p-Rb(S807/S811) | 73.52 | p-S6(S235/S236 | 355.93 | 2 | WM1552C-signal2 | C5 | |
| Vemurafenib | WM1552C | 0.1280 | uM | 24 | hr | | p-Histone H3(S10) | 230.57 | p-Rb(S807/S811) | 92.72 | p-S6(S235/S236 | 359.12 | 2 | WM1552C-signal2 | C6 | |
| Vemurafenib | WM1552C | 0.0512 | uM | 24 | hr | | p-Histone H3(S10) | 224.64 | p-Rb(S807/S811) | 95.99 | p-S6(S235/S236 | 373.81 | 2 | WM1552C-signal2 | C7 | |
| Vemurafenib | WM1552C | 0.0205 | uM | 24 | hr | | p-Histone H3(S10) | 223.26 | p-Rb(S807/S811) | 102.60 | p-S6(S235/S236 | 381.13 | 2 | WM1552C-signal2 | C8 | |
| Vemurafenib | WM1552C | 0.0082 | uM | 24 | hr | | p-Histone H3(S10) | 229.99 | p-Rb(S807/S811) | 110.00 | p-S6(S235/S236 | 389.09 | 2 | WM1552C-signal2 | C9 | |
| JNK-IN-8 | WM1552C | 0.0033 | uM | 24 | hr | | p-Histone H3(S10) | 237.82 | p-Rb(S807/S811) | 112.04 | p-S6(S235/S236 | 394.15 | 1 | WM1552C-signal2 | D10 | |
| JNK-IN-8 | WM1552C | 0.0000 | uM | 24 | hr | | p-Histone H3(S10) | 234.24 | p-Rb(S807/S811) | 115.31 | p-S6(S235/S236 | 377.79 | 1 | WM1552C-signal2 | D11 | |
| JNK-IN-8 | WM1552C | 5.0000 | uM | 24 | hr | | p-Histone H3(S10) | 236.28 | p-Rb(S807/S811) | 113.21 | p-S6(S235/S236 | 450.52 | 1 | WM1552C-signal2 | D2 | |
| JNK-IN-8 | WM1552C | 2.0000 | uM | 24 | hr | | p-Histone H3(S10) | 226.81 | p-Rb(S807/S811) | 116.31 | p-S6(S235/S236 | 435.53 | 1 | WM1552C-signal2 | D3 | |
| JNK-IN-8 | WM1552C | 0.8000 | uM | 24 | hr | | p-Histone H3(S10) | 262.28 | p-Rb(S807/S811) | 113.37 | p-S6(S235/S236 | 413.92 | 1 | WM1552C-signal2 | D4 |