Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | MAP3K3 | ELASKQVQFDPDSPETSKEVSALECEIQLLK | Lys1 | 9.754251417 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP3K4 | DIKGANIFLTSSGLIK | Lys2 | -8.019926684 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP3K5 | DIKGDNVLINTYSGVLK | Lys2 | -22.09265837 | 1 | uM |
| Ibrutinib | MWCL.1 | MARK2,MARK3 | DLKAENLLLDADMNIK | Lys2 | -34.96941065 | 1 | uM |
| Ibrutinib | MWCL.1 | MARK3 | EVAIKIIDKTQLNPTSLQK | Lys1 | 13.18511493 | 1 | uM |
| Ibrutinib | MWCL.1 | MARK3,MARK4 | EVAIKIIDK | Lys1 | 7.958081475 | 1 | uM |
| Ibrutinib | MWCL.1 | MAST1,MAST2 | DLKPDNLLITSMGHIK | Lys2 | -39.15099693 | 1 | uM |
| Ibrutinib | MWCL.1 | MAST3 | DLKPDNLLITSLGHIK | Lys2 | 11.76618134 | 1 | uM |
| Ibrutinib | MWCL.1 | MASTL | GAFGKVYLGQK | ATP Loop | 2.384864137 | 1 | uM |
| Ibrutinib | MWCL.1 | MASTL | LYAVKVVK | Lys1 | 2.531832127 | 1 | uM |
| Ibrutinib | MWCL.1 | MLK3 | DLKSNNILLLQPIESDDMEHK | Lys2 | -2.848870491 | 1 | uM |
| Ibrutinib | MWCL.1 | MLK4 | DLKSSNILLLEK | Lys2 | ND | 1 | uM |
| Ibrutinib | MWCL.1 | MLKL | APVAIKVFK | Lys1 | 2.471839009 | 1 | uM |
| Ibrutinib | MWCL.1 | MSK1_domain1 | DIKLENILLDSNGHVVLTDFGLSK | Lys2 | -5.356631539 | 1 | uM |
| Ibrutinib | MWCL.1 | MSK2 domain1 | DLKLENVLLDSEGHIVLTDFGLSK | Lys2 | -6.928886375 | 1 | uM |
| Ibrutinib | MWCL.1 | MST1 | ETGQIVAIKQVPVESDLQEIIK | Lys1 | 5.751494575 | 1 | uM |
| Ibrutinib | MWCL.1 | MST2 | ESGQVVAIKQVPVESDLQEIIK | Lys1 | 7.925363776 | 1 | uM |
| Ibrutinib | MWCL.1 | MST3 | DIKAANVLLSEHGEVK | Lys2 | 4.986768398 | 1 | uM |
| Ibrutinib | MWCL.1 | MST4 | TQQVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSSYVTK | Lys1 | 20.04245465 | 1 | uM |
| Ibrutinib | MWCL.1 | MST4,YSK1 | DIKAANVLLSEQGDVK | Lys2 | -3.600863518 | 1 | uM |
| Ibrutinib | MWCL.1 | MYO3A,MYO3B | DVKGNNILLTTEGGVK | Lys2 | -0.322018507 | 1 | uM |
| Ibrutinib | MWCL.1 | NDR1 | DIKPDNLLLDSK | Lys2 | -11.48077205 | 1 | uM |
| Ibrutinib | MWCL.1 | NDR2 | DIKPDNLLLDAK | Lys2 | 1.01286665 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK1 | DIKSQNIFLTK | Lys2 | -6.454049368 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK3 | SKNIFLTQNGK | Activation Loop | 7.904108301 | 1 | uM |