Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | IRAK4 | DIKSANILLDEAFTAK | Lys2 | -6.293666869 | 1 | uM |
| Ibrutinib | MWCL.1 | IRE1 | DLKPHNILISMPNAHGK | Lys2 | -26.21548408 | 1 | uM |
| Ibrutinib | MWCL.1 | ITPK1 | ESIFFNSHNVSKPESSSVLTELDKIEGVFERPSDEVIR | ATP | 21.22236351 | 1 | uM |
| Ibrutinib | MWCL.1 | JAK1 | QLASALSYLEDKDLVHGNVCTKNLLLAR | Other | -11.54958955 | 1 | uM |
| Ibrutinib | MWCL.1 | JAK1_domain2 | IGDFGLTKAIETDKEYYTVK | Activation Loop | -1.182963279 | 1 | uM |
| Ibrutinib | MWCL.1 | JAK3 domain2 | IADFGLAKLLPLDKDYYVVR | Activation Loop | -18.73992925 | 1 | uM |
| Ibrutinib | MWCL.1 | JNK1,JNK2,JNK3 | DLKPSNIVVK | Lys2 | 10.37416169 | 1 | uM |
| Ibrutinib | MWCL.1 | KHS1 | NVHTGELAAVKIIK | Lys1 | 3.149403179 | 1 | uM |
| Ibrutinib | MWCL.1 | KSR1,KSR2 | SKNVFYDNGK | Activation Loop | -0.502681471 | 1 | uM |
| Ibrutinib | MWCL.1 | LATS1 | ALYATKTLR | Lys1 | 30.59661536 | 1 | uM |
| Ibrutinib | MWCL.1 | LATS2 | DIKPDNILIDLDGHIK | Lys2 | 16.67405262 | 1 | uM |
| Ibrutinib | MWCL.1 | LKB1 | DIKPGNLLLTTGGTLK | Lys2 | -2.446050189 | 1 | uM |
| Ibrutinib | MWCL.1 | LOK | DLKAGNVLMTLEGDIR | Lys2 | -31.7274951 | 1 | uM |
| Ibrutinib | MWCL.1 | LRRK2 | DLKPHNVLLFTLYPNAAIIAK | Lys2 | 2.296798031 | 1 | uM |
| Ibrutinib | MWCL.1 | LYN | VAVKTLKPGTMSVQAFLEEANLMK | Lys1 | 53.9272985 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K1 | IMHRDVKPSNILVNSR | Lys2 | -30.9231499 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K1,MAP2K2 | DVKPSNILVNSR | Lys2 | -11.10881479 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K3 | DVKPSNVLINK | Lys2 | -0.499074082 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K4 | DIKPSNILLDR | Lys2 | -5.726078257 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K5 | DVKPSNMLVNTR | Lys2 | 52.87485319 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP2K6 | DVKPSNVLINALGQVK | Lys2 | 0.432117988 | 1 | uM |
| Ibrutinib | MWCL.1 | MP2K7 | DVKPSNILLDER | Lys2 | 34.78109475 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP3K1 | DVKGANLLIDSTGQR | Lys2 | 27.11649284 | 1 | uM |
| Ibrutinib | MWCL.1 | M3K2 | ELAVKQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | 8.927911177 | 1 | uM |
| Ibrutinib | MWCL.1 | M3K2,MAP3K3 | DIKGANILR | Lys2 | 12.7678829 | 1 | uM |