Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | PKD2 | DVAVKVIDK | Lys1 | -5.152720253 | 1 | uM |
| Ibrutinib | BCWM.1 | PKD3 | DVAIKVIDK | Lys1 | 8.235985053 | 1 | uM |
| Ibrutinib | BCWM.1 | PKN1 | VLLSEFRPSGELFAIKALK | Lys1 | -7.451256887 | 1 | uM |
| Ibrutinib | BCWM.1 | PKR | DLKPSNIFLVDTK | Lys2 | -15.97584338 | 1 | uM |
| Ibrutinib | BCWM.1 | PLK1 | CFEISDADTKEVFAGKIVPK | Lys1 | -3.592091178 | 1 | uM |
| Ibrutinib | BCWM.1 | PRP4 | CNILHADIKPDNILVNESK | Lys2 | -8.100671563 | 1 | uM |
| Ibrutinib | BCWM.1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 12.04805994 | 1 | uM |
| Ibrutinib | BCWM.1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | 5.185805758 | 1 | uM |
| Ibrutinib | BCWM.1 | RAF1 | DMKSNNIFLHEGLTVK | Lys2 | -27.17322941 | 1 | uM |
| Ibrutinib | BCWM.1 | RIPK2 | VQVAVKHLHIHTPLLDSER | Lys1 | 32.73183669 | 1 | uM |
| Ibrutinib | BCWM.1 | RIPK3 | DLKPSNVLLDPELHVK | Lys2 | -6.589809774 | 1 | uM |
| Ibrutinib | BCWM.1 | ROCK1,ROCK2 | DVKPDNMLLDK | Lys2 | -7.695044088 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK1 domain1 | DLKPENILLDEEGHIKLTDFGLSKEAIDHEK | Lys2 | 11.86811088 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK1_domain2 | DLKPSNILYVDESGNPECLR | Lys2 | -16.63379555 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK1,RSK2,RSK3_domain1 | DLKPENILLDEEGHIK | Lys2 | 15.17454184 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK2_domain2 | DLKPSNILYVDESGNPESIR | Lys2 | -9.478156165 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK3_domain1 | DLKPENILLDEEGHIKITDFGLSK | Lys2 | -17.68430721 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK4 domain1 | DLKPENILLDEIGHIK | Lys2 | 41.65622466 | 1 | uM |
| Ibrutinib | BCWM.1 | RSKL1_domain1 | VLGVIDKVLLVMDTR | ATP | -5.954087597 | 1 | uM |
| Ibrutinib | BCWM.1 | SGK3 | FYAVKVLQK | Lys1 | -4.187308779 | 1 | uM |
| Ibrutinib | BCWM.1 | SLK | DLKAGNILFTLDGDIK | Lys2 | -10.85031689 | 1 | uM |
| Ibrutinib | BCWM.1 | SMG1 | DTVTIHSVGGTITILPTKTKPK | ATP | -21.97910554 | 1 | uM |
| Ibrutinib | BCWM.1 | SNRK | DLKPENVVFFEK | Lys2 | 20.89644425 | 1 | uM |
| Ibrutinib | BCWM.1 | SRPK1 | IIHTDIKPENILLSVNEQYIR | Lys2 | -15.61332699 | 1 | uM |
| Ibrutinib | BCWM.1 | SRPK1/2 | FVAMKVVK | Lys1 | -36.60555534 | 1 | uM |