Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | STLK5 | YSVKVLPWLSPEVLQQNLQGYDAK | Activation Loop | -6.616759843 | 1 | uM |
| Ibrutinib | BCWM.1 | STLK6 | HTPTGTLVTIKITNLENCNEER | Lys1 | ND | 1 | uM |
| Ibrutinib | BCWM.1 | SYK | ISDFGLSKALR | Activation Loop | 4.99092358 | 1 | uM |
| Ibrutinib | BCWM.1 | MAP3K7,TAK1 | DLKPPNLLLVAGGTVLK | Lys2 | -22.92398178 | 1 | uM |
| Ibrutinib | BCWM.1 | TAO1,TAOK3 | DIKAGNILLTEPGQVK | Lys2 | 8.693117708 | 1 | uM |
| Ibrutinib | BCWM.1 | TAOK2 | DVKAGNILLSEPGLVK | Lys2 | 10.55619889 | 1 | uM |
| Ibrutinib | BCWM.1 | TBK1 | TGDLFAIKVFNNISFLRPVDVQMR | Lys1 | -3.579567634 | 1 | uM |
| Ibrutinib | BCWM.1 | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | > 87 | 1 | uM |
| Ibrutinib | BCWM.1 | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | 10.62242227 | 1 | uM |
| Ibrutinib | BCWM.1 | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | 11.88568593 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -0.802332312 | 1 | uM |
| Ibrutinib | BCWM.1 | ULK3 | NISHLDLKPQNILLSSLEKPHLK | Lys2 | -0.055167396 | 1 | uM |
| Ibrutinib | BCWM.1 | VRK2 | MLDVLEYIHENEYVHGDIKAANLLLGYK | Lys2 | -13.00273003 | 1 | uM |
| Ibrutinib | BCWM.1 | WEE1 | YIHSMSLVHMDIKPSNIFISR | Lys2 | -66.07854902 | 1 | uM |
| Ibrutinib | BCWM.1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | -0.449832509 | 1 | uM |
| Ibrutinib | BCWM.1 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | 5.566332997 | 1 | uM |
| Ibrutinib | BCWM.1 | ZC2/TNIK | TGQLAAIKVMDVTGDEEEEIKQEINMLKK | Lys1 | -51.1480675 | 1 | uM |
| Ibrutinib | BCWM.1 | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | > 60 | 1 | uM |
| Ibrutinib | BCWM.1 | KCC2D | IPTGQEYAAKIINTKK | Lys1 | -7.979482453 | 1 | uM |
| Ibrutinib | BCWM.1 | KCC4 | DLKPENLLYATPAPDAPLK | Lys2 | -15.13874098 | 1 | uM |
| Ibrutinib | BCWM.1 | KC1G2 | DVKPENFLVGRPGTK | Lys2 | 15.93108027 | 1 | uM |
| Ibrutinib | BCWM.1 | EPHB1 | YLQDDTSDPTYTSSLGGKIPVR | Activation Loop | -6.229612864 | 1 | uM |
| Ibrutinib | BCWM.1 | MK01 | DLKPSNLLLNTTCDLK | Lys2 | 7.812118863 | 1 | uM |
| Ibrutinib | BCWM.1 | FRK | HEIKLPVK | Activation Loop | 19.65136769 | 1 | uM |
| Ibrutinib | BCWM.1 | KSR1 | SKNVFYDNGKVVITDFGLFGISGVVR | Activation Loop | -0.005640215 | 1 | uM |