Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | BCWM.1 | LCK | EGAKFPIKWTAPEAINYGTFTIK | Activation Loop | 41.87826759 | 1 | uM |
| Ibrutinib | BCWM.1 | M3K6 | DIKGDNVLINTFSGLLK | Lys2 | -18.14146781 | 1 | uM |
| Ibrutinib | BCWM.1 | MARK4 | DLKAENLLLDAEANIK | Lys2 | -11.00743851 | 1 | uM |
| Ibrutinib | BCWM.1 | MELK | DLKPENLLFDEYHK | Lys2 | -6.492711736 | 1 | uM |
| Ibrutinib | BCWM.1 | NEK2 | DLKPANVFLDGK | Lys2 | 20.31739372 | 1 | uM |
| Ibrutinib | BCWM.1 | CDK16 | SKLTDNLVALKEIR | Lys1 | -26.55786151 | 1 | uM |
| Ibrutinib | BCWM.1 | RSK2 domain1 | DLKPENILLDEEGHIKLTDFGLSKESIDHEK | Lys2 | 20.13948334 | 1 | uM |
| Ibrutinib | BCWM.1 | STK33 | DLKLENIMVK | Lys2 | -32.70330347 | 1 | uM |
| Ibrutinib | BCWM.1 | TYK2(Kin.Dom.2) | IGDFGLAKAVPEGHEYYR | Activation Loop | 1.129238559 | 1 | uM |
| Ibrutinib | BCWM.1 | Wnk1,Wnk2 | GSFKTVYK | ATP Loop | -10.02684253 | 1 | uM |
| Ibrutinib | MWCL.1 | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | ND | 1 | uM |
| Ibrutinib | MWCL.1 | KCC2D | IPTGQEYAAKIINTKK | Lys1 | 2.95906396 | 1 | uM |
| Ibrutinib | MWCL.1 | KCC4 | DLKPENLLYATPAPDAPLK | Lys2 | 4.886400505 | 1 | uM |
| Ibrutinib | MWCL.1 | KC1G2 | DVKPENFLVGRPGTK | Lys2 | -3.63205455 | 1 | uM |
| Ibrutinib | MWCL.1 | EPHB1 | YLQDDTSDPTYTSSLGGKIPVR | Activation Loop | ND | 1 | uM |
| Ibrutinib | MWCL.1 | MK01 | DLKPSNLLLNTTCDLK | Lys2 | -5.228916451 | 1 | uM |
| Ibrutinib | MWCL.1 | FRK | HEIKLPVK | Activation Loop | 54.56199019 | 1 | uM |
| Ibrutinib | MWCL.1 | KSR1 | SKNVFYDNGKVVITDFGLFGISGVVR | Activation Loop | -1.14806106 | 1 | uM |
| Ibrutinib | MWCL.1 | LCK | EGAKFPIKWTAPEAINYGTFTIK | Activation Loop | 77.85191858 | 1 | uM |
| Ibrutinib | MWCL.1 | M3K6 | DIKGDNVLINTFSGLLK | Lys2 | ND | 1 | uM |
| Ibrutinib | MWCL.1 | MARK4 | DLKAENLLLDAEANIK | Lys2 | -55.47831427 | 1 | uM |
| Ibrutinib | MWCL.1 | MELK | DLKPENLLFDEYHK | Lys2 | 15.93032626 | 1 | uM |
| Ibrutinib | MWCL.1 | NEK2 | DLKPANVFLDGK | Lys2 | -0.76249132 | 1 | uM |
| Ibrutinib | MWCL.1 | CDK16 | SKLTDNLVALKEIR | Lys1 | -2.202969283 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK2 domain1 | DLKPENILLDEEGHIKLTDFGLSKESIDHEK | Lys2 | 4.015033615 | 1 | uM |