Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| MK2206 | T47D | 10.0 | uM | 24 | hr | 173.79 | 52.31 | p-S6 | 39.86 | |
| Triciribine | T47D | 10.0 | uM | 6 | hr | 110.45 | 41.24 | p-S6 | 39.23 | |
| Triciribine | T47D | 10.0 | uM | 24 | hr | 170.17 | 66.91 | p-S6 | 405.92 | |
| Dactolisib | T47D | 10.0 | uM | 6 | hr | 88.85 | 36.94 | p-S6 | 4.07 | |
| Dactolisib | T47D | 10.0 | uM | 24 | hr | 137.63 | 102.12 | p-S6 | 6.93 | |