Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Baicalein | LY2 | -3.7773 | 0.9212 | -4.2757 | -4.2757 | -4.5538 | 2.7820 | 0.0000 | 0.0394 | 8.2800 |
| Baicalein | ZR75B | -3.7773 | 0.8631 | -4.4547 | -3.7773 | -4.2948 | 1.2830 | 0.4492 | 0.5148 | 8.0720 |
| Olomoucine II | MCF7 | -3.8761 | 0.9680 | -5.1651 | -5.1401 | -5.2450 | 3.6090 | 0.0935 | 0.0935 | 6.7612 |
| Olomoucine II | SK-BR-3 | -3.8761 | 0.9637 | -4.9591 | -4.9362 | -5.0440 | 3.4280 | 0.0838 | 0.0840 | 7.1638 |
| Olomoucine II | MDA-MB-231 | -3.8761 | 0.7196 | -4.9011 | -4.8569 | -4.8980 | 3.9920 | 0.1675 | 0.1676 | 8.6571 |
| Olomoucine II | AU565 | -3.8761 | 0.9448 | -5.3221 | -5.3181 | -5.3977 | 4.0000 | 0.0164 | 0.0164 | 6.4289 |
| Olomoucine II | BT-20 | -3.8761 | 0.9596 | -5.1661 | -5.0814 | -5.4342 | 1.3285 | 0.1148 | 0.1327 | 6.9706 |
| Olomoucine II | BT-474 | -3.8761 | 0.8243 | -5.3131 | -4.9084 | -5.3440 | 3.9960 | 0.4879 | 0.4879 | 8.2281 |
| Olomoucine II | BT-483 | -3.8761 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.7478 |
| Olomoucine II | BT-549 | -3.8761 | 0.9558 | -5.6701 | -5.6198 | -5.7029 | 1.5420 | 0.0813 | 0.0829 | 6.3945 |
| Olomoucine II | CAMA-1 | -3.8761 | 0.9500 | -4.9836 | -4.8948 | -5.3226 | 1.5335 | 0.1283 | 0.1466 | 7.0928 |
| Olomoucine II | HCC1143 | -3.8761 | 0.9102 | -5.3781 | -5.3472 | -5.5299 | 1.4020 | 0.0479 | 0.0553 | 6.5306 |
| Olomoucine II | HCC1395 | -3.8761 | 0.9510 | -5.2126 | -5.1987 | -5.7478 | 0.9758 | 0.0122 | 0.0696 | 6.5818 |
| Olomoucine II | HCC1419 | -3.8761 | 0.8205 | -4.8563 | -4.5755 | -5.4150 | 0.9757 | 0.2339 | 0.3102 | 7.3462 |
| Olomoucine II | HCC1428 | -3.8761 | 0.9205 | -5.0086 | -4.6896 | -5.3374 | 1.0836 | 0.2494 | 0.2964 | 7.2530 |
| Olomoucine II | HCC1569 | -3.8761 | 0.9495 | -5.2511 | -4.4690 | -5.3120 | 2.5615 | 0.3647 | 0.3757 | 7.3912 |
| Olomoucine II | HCC1806 | -3.8761 | 0.9880 | -5.0531 | -5.0427 | -5.1219 | 2.8730 | 0.0327 | 0.0331 | 6.8721 |
| Olomoucine II | HCC1937 | -3.8761 | 0.9265 | -5.0781 | -4.9966 | -5.1173 | 3.9550 | 0.2611 | 0.2611 | 7.6280 |
| Olomoucine II | HCC1954 | -3.8761 | 0.9483 | -5.0281 | -4.9436 | -5.0528 | 3.3400 | 0.2385 | 0.2386 | 7.3086 |
| Olomoucine II | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Olomoucine II | HCC38 | -3.8761 | 0.9529 | -5.4671 | -5.4498 | -5.5914 | 1.4830 | 0.0285 | 0.0327 | 6.1038 |
| Olomoucine II | HCC70 | -3.8761 | 0.9773 | -5.2351 | -5.2353 | -5.4698 | 1.7585 | 0.0000 | 0.0041 | 6.2929 |
| Olomoucine II | Hs 578T | -3.8761 | 0.9357 | -5.0601 | -4.9549 | -5.2092 | 0.7147 | 0.0796 | 0.1944 | 6.9026 |
| Olomoucine II | MB 157 | -3.8761 | 0.9859 | -5.1941 | -5.1370 | -5.1962 | 3.9980 | 0.2032 | 0.2032 | 7.2610 |
| Olomoucine II | MDA-MB-134-VI | -3.8761 | 0.9010 | -5.1556 | -4.9295 | -5.2018 | 3.9990 | 0.4163 | 0.4163 | 7.7690 |