NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| NVP-BHG712 | PC-3 | DGKH | ATFSFCVSPLLVFVNSkSGDNQGVK | ATP | -83.6 | 0.05 | uM |
| NVP-BHG712 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 26.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | -6.3 | 0.05 | uM |
| NVP-BHG712 | PC-3 | eEF2K | YIkYNSNSGFVR | ATP | 10.4 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EGFR | ITDFGLAkLLGAEEK | Activation Loop | 10.8 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EGFR | LLGAEEKEYHAEGGkVPIK | Activation Loop | -16.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EGFR | IPVAIkELR | Lys1 | 8.1 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EphA1 | LLDDFDGTYETQGGkIPIR | Activation Loop | 26.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 83.1 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EPHA2 | EVPVAIkTLK | Lys1 | 73.8 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EphA7 | VIEDDPEAVYTTTGGkIPVR | Activation Loop | 23.3 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EPHB2 | FLEDDTSDPTYTSALGGkIPIR | Activation Loop | 92.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | EPHB4 | FLEENSSDPTYTSSLGGkIPIR | Activation Loop | 82.5 | 0.05 | uM |
| NVP-BHG712 | PC-3 | MK03 | YIHSANVLHRDLkPSNLLINTTCDLK | Lys2 | -37.1 | 0.05 | uM |
| NVP-BHG712 | PC-3 | MK03 | DLkPSNLLINTTCDLK | Lys2 | 1.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | MK01 | YIHSANVLHRDLkPSNLLLNTTCDLK | Lys2 | -48.0 | 0.05 | uM |
| NVP-BHG712 | PC-3 | Erk5 | DLkPSNLLVNENCELK | Lys2 | 1.4 | 0.05 | uM |
| NVP-BHG712 | PC-3 | FAK | CIGEGQFGDVHQGIYMSPENPALAVAIkTCK | Lys1 | -1.6 | 0.05 | uM |
| NVP-BHG712 | PC-3 | FER | QEDGGVYSSSGLkQIPIK | Activation Loop | 5.4 | 0.05 | uM |
| NVP-BHG712 | PC-3 | FER | TSVAVkTCKEDLPQELK | Lys1 | -15.7 | 0.05 | uM |
| NVP-BHG712 | PC-3 | FRAP1 | IQSIAPSLQVITSkQRPR | ATP | -16.9 | 0.05 | uM |
| NVP-BHG712 | PC-3 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | -3.4 | 0.05 | uM |
| NVP-BHG712 | PC-3 | GCK | DTVTSELAAVkIVK | Lys1 | 5.7 | 0.05 | uM |
| NVP-BHG712 | PC-3 | GCK | DIkGANLLLTLQGDVK | Lys2 | -2.7 | 0.05 | uM |
| NVP-BHG712 | PC-3 | GCN2_domain2 | VQNKLDGCCYAVkR | Lys1 | -2.5 | 0.05 | uM |