NVP-BHG712 KiNativ -- multiple dose experiment - Dataset (ID:20104)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| NVP-BHG712 | PC-3 | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | 80.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ACK | TVSVAVkCLKPDVLSQPEAMDDFIR | Lys1 | 25.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AGK | ATVFLNPAACkGK | ATP | -6.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AMPKa1 | IGHYILGDTLGVGTFGkVK | ATP Loop | 12.9 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | 13.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | 23.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AMPKa2 | IGHYVLGDTLGVGTFGkVK | ATP Loop | 5.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ARAF | DLkSNNIFLHEGLTVK | Lys2 | 9.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ATR | FYIMMCkPK | ATP | 5.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | ATR | kAGHHQTAYNALLNAGESR | Protein Kinase Domain | 14.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AurA | FILALkVLFK | Lys1 | -0.7 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AurA | DIkPENLLLGSAGELK | Lys2 | 4.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | AurB | SHFIVALkVLFK | Lys1 | 9.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | BARK1 | DLkPANILLDEHGHVR | Lys2 | -12.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | BCKDK | QLLDDHkDVVTLLAEGLR | Other | 0.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | BRAF | DLkSNNIFLHEDLTVK | Lys2 | 80.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CaMK1a | LVAIkCIAK | Lys1 | -3.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CAMK1D | LFAVkCIPK | Lys1 | -3.1 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CaMK2a,CaMK2b,CaMK2d,CaMK2g | DLkPENLLLASK | Lys2 | -9.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | KCC2D | IPTGQEYAAkIINTK | Lys1 | 4.8 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CaMK2g | TSTQEYAAkIINTK | Lys1 | 14.0 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CaMK2g | KTSTQEYAAkIINTKK | Lys1 | 3.3 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CASK | ETGQQFAVkIVDVAK | Lys1 | 5.6 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDC2 | DLkPQNLLIDDKGTIK | Lys2 | 3.4 | 5.00 | uM |
| NVP-BHG712 | PC-3 | CDK11,CDK8 | DLkPANILVMGEGPER | Lys2 | 36.8 | 5.00 | uM |