PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | IC50 | Conc unit |
|---|---|---|---|---|---|---|
| PLX-4720 | A-375 | PIK3C3 | TEDGGKYPVIFkHGDDLRQDQLILQIISLMDK | ATP | 8.5 | uM |
| PLX-4720 | A-375 | IRAK1 | AIQFLHQDSPSLIHGDIkSSNVLLDER | LYS2 | 7.6 | uM |
| PLX-4720 | A-375 | AurA,AurB,AurC | GkFGNVYLAR | ATP Loop | 7.2 | uM |
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 6.4 | uM |
| PLX-4720 | A-375 | GCN2_domain2 | DLkPVNIFLDSDDHVK | LYS2 | 6.4 | uM |
| PLX-4720 | A-375 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 6.2 | uM |
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVKWTAPEALR | Activation Loop | 6.1 | uM |
| PLX-4720 | A-375 | MAP2K4 | MVHKPSGQIMAVkR | LYS1 | 5.6 | uM |
| PLX-4720 | A-375 | KHS1 | DIkGANILLTDHGDVKLADFGVAAK | LYS2 | 5.2 | uM |
| PLX-4720 | A-375 | MLKL | APVAIkVFK | LYS1 | 4.9 | uM |
| PLX-4720 | A-375 | KHS1 | DIkGANILLTDHGDVK | LYS2 | 4.7 | uM |
| PLX-4720 | A-375 | SRC | VAIkTLKPGTMSPEAFLQEAQVMKK | LYS1 | 4.7 | uM |
| PLX-4720 | A-375 | GCK | DTVTSELAAVkIVK | LYS1 | 4.0 | uM |
| PLX-4720 | A-375 | GCN2_domain2 | VQNKLDGCCYAVkR | LYS1 | 3.9 | uM |
| PLX-4720 | A-375 | SRC | VAIkTLKPGTMSPEAFLQEAQVMK | LYS1 | 3.5 | uM |
| PLX-4720 | A-375 | MAP3K1 | DVkGANLLIDSTGQR | LYS2 | 3.2 | uM |
| PLX-4720 | A-375 | KHS1 | NVHTGELAAVkIIK | LYS1 | 3.2 | uM |
| PLX-4720 | A-375 | LRRK2 | DLkPHNVLLFTLYPNAAIIAK | LYS2 | 3.2 | uM |
| PLX-4720 | A-375 | ZC1/HGK | TGQLAAIkVMDVTEDEEEEIKLEINMLK | LYS1 | 2.2 | uM |
| PLX-4720 | A-375 | ZC2/TNIK,ZC3/MINK | VIHRDIkGQNVLLTENAEVK | LYS2 | 2.0 | uM |
| PLX-4720 | A-375 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIkGQNVLLTENAEVK | LYS2 | 2.0 | uM |
| PLX-4720 | A-375 | CDK11,CDK8 | DLkPANILVMGEGPER | LYS2 | 1.7 | uM |
| PLX-4720 | A-375 | MAP2K1 | IMHRDVkPSNILVNSR | LYS2 | 13.0 | uM |
| PLX-4720 | A-375 | CaMK1a | LVAIkCIAK | LYS1 | 13.0 | uM |
| PLX-4720 | A-375 | MAP2K1,MAP2K2 | DVkPSNILVNSR | LYS2 | 12.0 | uM |