PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | IC50 | Conc unit |
|---|---|---|---|---|---|---|
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVKWTAPEALR | Activation Loop | 6.1 | uM |
| PLX-4720 | A-375 | RSK2_domain1 | LTDFGLSkESIDHEKK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | RSK1_domain1 | LTDFGLSkEAIDHEKK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | JAK1_domain2 | IGDFGLTkAIETDKEYYTVK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | NEK9 | LGDYGLAkK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | FER | QEDGGVYSSSGLkQIPIKWTAPEALNYGR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 6.2 | uM |
| PLX-4720 | A-375 | KS6B2 | LTDFGLCkESIHEGAVTHTFCGTIEYMAPEILVR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | Wnk1,Wnk2,Wnk4 | IGDLGLATLkR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | NDR1,NDR2 | LSDFGLCTGLkK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | NEK7 | FFSSkTTAAHSLVGTPYYMSPER | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | AXL | NCMLNENMSVCVADFGLSkK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | MAP2K6 | MCDFGISGYLVDSVAkTIDAGCKPYMAPER | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | 0.83 | uM |
| PLX-4720 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 6.4 | uM |
| PLX-4720 | A-375 | MST3,MST4,YSK1 | LADFGVAGQLTDTQIkR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | KS6B1 | LTDFGLCkESIHDGTVTHTFCGTIEYMAPEILMR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | DNAPK | kGGSWIQEINVAEK | ATP | >10 | uM |
| PLX-4720 | A-375 | ITPK1 | ESIFFNSHNVSkPESSSVLTELDKIEGVFERPSDEVIR | ATP | >10 | uM |
| PLX-4720 | A-375 | ATR | FYIMMCkPK | ATP | >10 | uM |
| PLX-4720 | A-375 | AGK | ATVFLNPAACkGK | ATP | >10 | uM |
| PLX-4720 | A-375 | ATM | QLVkGRDDLRQDAVMQQVFQMCNTLLQR | ATP | >10 | uM |
| PLX-4720 | A-375 | DNAPK | GHDEREHPFLVkGGEDLR | ATP | >10 | uM |