PLX-4720 KiNativ -- dose response experiment - Dataset (ID:20090)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | IC50 | Conc unit |
|---|---|---|---|---|---|---|
| PLX-4720 | A-375 | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | 0.83 | uM |
| PLX-4720 | A-375 | ABL,ARG | YSLTVAVkTLKEDTMEVEEFLK | LYS1 | 0.33 | uM |
| PLX-4720 | A-375 | ACK | TVSVAVKCLkPDVLSQPEAMDDFIR | LYS1 | 0.22 | uM |
| PLX-4720 | A-375 | AGK | ATVFLNPAACkGK | ATP | >10 | uM |
| PLX-4720 | A-375 | AKT1 | GTFGkVILVK | ATP Loop | >10 | uM |
| PLX-4720 | A-375 | AKT2,AKT3 | GTFGkVILVR | ATP Loop | >10 | uM |
| PLX-4720 | A-375 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | AMPKa1,AMPKa2 | VAVkILNR | LYS1 | >10 | uM |
| PLX-4720 | A-375 | ARAF | DLkSNNIFLHEGLTVK | LYS2 | 0.022 | uM |
| PLX-4720 | A-375 | ATM | QLVkGRDDLRQDAVMQQVFQMCNTLLQR | ATP | >10 | uM |
| PLX-4720 | A-375 | ATR | FYIMMCkPK | ATP | >10 | uM |
| PLX-4720 | A-375 | AurA | DIkPENLLLGSAGELK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | AurA,AurB,AurC | GkFGNVYLAR | ATP Loop | 7.2 | uM |
| PLX-4720 | A-375 | AXL | NCMLNENMSVCVADFGLSkK | Activation Loop | >10 | uM |
| PLX-4720 | A-375 | BRAF | DLkSNNIFLHEDLTVK | LYS2 | 0.0077 | uM |
| PLX-4720 | A-375 | CaMK1a | LVAIkCIAK | LYS1 | 13.0 | uM |
| PLX-4720 | A-375 | KCC2D | IPTGQEYAAkIINTK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CaMK2g | TSTQEYAAkIINTK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CaMK2g | KTSTQEYAAkIINTKK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CaMKK2 | LAYNENDNTYYAMkVLSK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CASK | ETGQQFAVkIVDVAK | LYS1 | >10 | uM |
| PLX-4720 | A-375 | CDC2 | DLkPQNLLIDDKGTIK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK10 | DLkVSNLLMTDK | LYS2 | >10 | uM |
| PLX-4720 | A-375 | CDK11,CDK8 | DLkPANILVMGEGPER | LYS2 | 1.7 | uM |
| PLX-4720 | A-375 | CDK2 | NKLTGEVVALkK | LYS1 | >10 | uM |