Growth rate-corrected (GR) dose-response metric signatures across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 3 of 4: Median, upper quartile, and lower quartile GR metrics per perturbagen. - Dataset (ID:20270)

Small Molecules Studied

HMS LINCS ID Name Alternative Names LINCS ID Structure Image PubChem CID
10110-3 FR180204
FR 180204; KIN001-230
LSM-42790 11493598
10259-1 ICRF-193 LSM-4280 115150
10175-3 Sunitinib
Sutent; SU11248
LSM-42800 3086686
10262-1 L-779450 LSM-4283 9950176
10263-1 LBH589
Panobinostat
LSM-4284 57519507
10267-1 NU6102 LSM-4287 4566
10270-1 Oxamflatin LSM-4290 4611
10274-1 SB-3CT LSM-4293 9883002
10277-1 Temsirolimus LSM-4295 148191
10283-1 XRP44X
AG-G-87906
LSM-4298 10339779
10279-1 Trichostatin A LSM-43005
10133-2 Afatinib
BIBW-2992
LSM-43226 57519523
10236-1 17-AAG
Tanespimycin
LSM-43239 151069
10261-1 Ixabepilone
Azaepothilone B; Ixempra
LSM-43293 216344
10275-1 (Z)-4-Hydroxytamoxifen LSM-43294 53770298
10269-1 Oxaliplatin
Eloxatin
LSM-44941 5310940
10242-1 Carboplatin LSM-44959 5237030
10346-1 Valproic acid
Depakine
LSM-4620 3549980
10252-1 Gemcitabine
Gemzar
LSM-5333 60750
10278-1 Topotecan
Hycamtin
LSM-5662 60700
10264-1 Methotrexate
Rheumatrex; Trexall; Amethopterin; MTX
LSM-5690 126941
10260-1 Ispinesib
SB-715992
LSM-5732 6851740
10265-1 Pevonedistat
MLN 4924; MLN-4924; MLN4924
LSM-6263 16720766
10241-4 Bortezomib
Velcade
LSM-6281 387447
10241-1 Bortezomib
Velcade
LSM-6281 387447