LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | AZD7762 | 0.37 | uM | LJP6 | 0.3195 | 0.0178 | -0.1682 | 0.1001 |
| SK-BR-3 | AZD8055 | 3.33 | uM | LJP6 | 0.3345 | 0.0157 | -0.1367 | 0.0703 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 0.8063 | 0.1043 | 0.7174 | 0.1376 |
| SK-BR-3 | AZD7762 | 0.12 | uM | LJP6 | 0.3491 | 0.0186 | -0.1103 | 0.1079 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 0.3843 | 0.0240 | -0.0402 | 0.0768 |
| SK-BR-3 | AZD8055 | 1.11 | uM | LJP6 | 0.3428 | 0.0148 | -0.1201 | 0.0576 |
| SK-BR-3 | Seliciclib | 0.37 | uM | LJP5 | 0.9839 | 0.0359 | 0.9793 | 0.0491 |
| SK-BR-3 | Seliciclib | 10 | uM | LJP5 | 0.4714 | 0.0484 | 0.1464 | 0.1021 |
| SK-BR-3 | AT-7519 | 1.11 | uM | LJP6 | 0.2620 | 0.0279 | -0.2840 | 0.0893 |
| SK-BR-3 | AZD7762 | 0.04 | uM | LJP6 | 0.4144 | 0.0239 | 0.0117 | 0.1164 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 0.2537 | 0.0104 | -0.3011 | 0.0810 |
| SK-BR-3 | AZD7762 | 10 | uM | LJP6 | 0.2350 | 0.0199 | -0.3411 | 0.0735 |
| SK-BR-3 | AZD8055 | 0.12 | uM | LJP6 | 0.3589 | 0.0242 | -0.0898 | 0.0982 |
| SK-BR-3 | AZD8055 | 0.37 | uM | LJP6 | 0.3537 | 0.0257 | -0.0997 | 0.0897 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 1.0292 | 0.0378 | 1.0436 | 0.0539 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 1.0266 | 0.0181 | 1.0411 | 0.0257 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 0.8990 | 0.0198 | 0.8522 | 0.0246 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 0.7857 | 0.0193 | 0.6774 | 0.0131 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 0.4778 | 0.0707 | 0.1403 | 0.0626 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 0.3511 | 0.0348 | -0.1037 | 0.0430 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 0.2036 | 0.0339 | -0.4099 | 0.1026 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 0.1546 | 0.0321 | -0.5234 | 0.0914 |
| SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 0.2672 | 0.0113 | -0.2725 | 0.0899 |
| SK-BR-3 | Sorafenib | 0.04 | uM | LJP6 | 0.9368 | 0.0202 | 0.9080 | 0.0277 |
| SK-BR-3 | AZD8055 | 10 | uM | LJP6 | 0.2315 | 0.0626 | -0.3633 | 0.0870 |