LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
Hs 578T Alpelisib
0.12
uM
LJP5
0.9115 0.0090 0.9151 0.0006
MCF 10A XL147
0.04
uM
LJP5
1.0241 0.0040 1.0136 0.0007
Hs 578T Pelitinib
0.04
uM
LJP5
0.9926 0.0014 0.9931 0.0008
MCF 10A CP724714
3.33
uM
LJP5
0.9742 0.0018 0.9849 0.0009
SK-BR-3 Selumetinib
0.04
uM
LJP6
1.0915 0.0101 1.1386 0.0009
MCF 10A Imatinib
0.12
uM
LJP6
1.0012 0.0023 1.0009 0.0013
MCF 10A BX-912
0.04
uM
LJP5
0.9161 0.0097 0.9500 0.0013
Hs 578T Neratinib
0.04
uM
LJP5
0.8831 0.0129 0.8870 0.0013
BT-20 PD184352
1.11
uM
LJP5
0.9888 0.0012 0.9868 0.0013
MCF 10A PD173074
0.12
uM
LJP6
1.0089 0.0015 1.0053 0.0014
Hs 578T PHA-665752
0.12
uM
LJP5
1.0022 0.0018 1.0023 0.0017
MCF 10A CP724714
10
uM
LJP5
0.8963 0.0152 0.9384 0.0017
MCF 10A Imatinib
0.37
uM
LJP6
0.9943 0.0021 0.9962 0.0017
Hs 578T SU11274
0.37
uM
LJP5
0.9468 0.0041 0.9492 0.0018
MCF 10A PD173074
0.04
uM
LJP6
1.0379 0.0026 1.0217 0.0018
MCF 10A LDN-193189
0.12
uM
LJP5
0.9678 0.0071 0.9817 0.0019
Hs 578T Gefitinib
3.33
uM
LJP6
0.9865 0.0020 0.9870 0.0020
BT-20 Seliciclib
0.12
uM
LJP5
0.9975 0.0017 0.9967 0.0020
Hs 578T Ruxolitinib
1.11
uM
LJP5
0.9515 0.0032 0.9536 0.0020
MCF 10A NU7441
0.12
uM
LJP5
1.0027 0.0032 1.0010 0.0021
MCF 10A CP724714
0.04
uM
LJP5
1.0194 0.0045 1.0105 0.0021
MCF7 JW-7-24-1
10
uM
LJP6
0.2219 0.0139 -0.1348 0.0021
Hs 578T MK2206
0.04
uM
LJP6
0.8911 0.0112 0.8934 0.0021
Hs 578T Gefitinib
0.12
uM
LJP6
0.9835 0.0028 0.9844 0.0021
MCF7 Buparlisib
3.33
uM
LJP5
0.1836 0.0164 -0.1880 0.0021
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