LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 0.0768 | 0.0374 | -0.7340 | 0.1000 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 0.0916 | 0.0421 | -0.6796 | 0.1080 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 0.0604 | 0.0240 | -0.5983 | 0.1051 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 0.0567 | 0.0226 | -0.5809 | 0.0944 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 0.0659 | 0.0380 | -0.5259 | 0.1101 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 0.1546 | 0.0321 | -0.5234 | 0.0914 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 0.1460 | 0.0150 | -0.5146 | 0.0624 |
| BT-20 | LDN-193189 | 10 | uM | LJP5 | 0.0934 | 0.0212 | -0.5070 | 0.0475 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 0.0733 | 0.0260 | -0.5038 | 0.1167 |
| BT-20 | A443654 | 10 | uM | LJP6 | 0.0999 | 0.0203 | -0.5029 | 0.0860 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 0.0738 | 0.0393 | -0.4960 | 0.1074 |
| BT-20 | CGP60474 | 10 | uM | LJP6 | 0.1043 | 0.0168 | -0.4889 | 0.0743 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP6 | 0.1685 | 0.0189 | -0.4855 | 0.0978 |
| MCF7 | CGP60474 | 10 | uM | LJP6 | 0.0894 | 0.0185 | -0.4845 | 0.0358 |
| BT-20 | Mitoxantrone | 10 | uM | LJP5 | 0.1078 | 0.0428 | -0.4782 | 0.1274 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 0.0901 | 0.0395 | -0.4565 | 0.1543 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 0.1816 | 0.0260 | -0.4536 | 0.1251 |
| SK-BR-3 | HG-6-64-01 | 10 | uM | LJP6 | 0.1866 | 0.0315 | -0.4531 | 0.0432 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 0.1822 | 0.0251 | -0.4527 | 0.1156 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 0.1722 | 0.0206 | -0.4505 | 0.1065 |
| BT-20 | GSK1059615 | 10 | uM | LJP6 | 0.1196 | 0.0220 | -0.4462 | 0.0835 |
| BT-20 | Mitoxantrone | 10 | uM | LJP6 | 0.1247 | 0.0355 | -0.4439 | 0.0959 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 0.1074 | 0.0350 | -0.4385 | 0.0834 |
| BT-20 | GSK1059615 | 10 | uM | LJP5 | 0.1158 | 0.0135 | -0.4335 | 0.0401 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 0.1937 | 0.0065 | -0.4312 | 0.0608 |