LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
Hs 578T Canertinib
1.11
uM
LJP6
0.9427 0.0011 0.9435 0.0063
BT-20 PD184352
1.11
uM
LJP5
0.9888 0.0012 0.9868 0.0013
MDA-MB-231 AZD8330
1.11
uM
LJP5
0.2961 0.0012 0.0698 0.0077
Hs 578T Pelitinib
0.04
uM
LJP5
0.9926 0.0014 0.9931 0.0008
Hs 578T Y39983
3.33
uM
LJP6
0.6510 0.0014 0.6259 0.0311
MCF 10A GW843682X
10
uM
LJP6
0.0642 0.0015 -0.1012 0.0992
MCF 10A PD173074
0.12
uM
LJP6
1.0089 0.0015 1.0053 0.0014
BT-20 PIK-93
10
uM
LJP5
0.3561 0.0016 0.0954 0.0256
BT-20 Seliciclib
0.12
uM
LJP5
0.9975 0.0017 0.9967 0.0020
MCF 10A PHA-665752
0.12
uM
LJP5
0.9713 0.0017 0.9827 0.0026
SK-BR-3 Tozasertib
0.04
uM
LJP5
0.3153 0.0018 -0.1428 0.0652
MCF 10A CP724714
3.33
uM
LJP5
0.9742 0.0018 0.9849 0.0009
SK-BR-3 Tozasertib
3.33
uM
LJP5
0.3411 0.0018 -0.0918 0.0596
Hs 578T PHA-665752
0.12
uM
LJP5
1.0022 0.0018 1.0023 0.0017
SK-BR-3 Sirolimus
10
uM
LJP6
0.6035 0.0019 0.3530 0.0586
Hs 578T Lapatinib
0.12
uM
LJP6
0.9750 0.0019 0.9754 0.0042
SK-BR-3 Dasatinib
0.12
uM
LJP6
0.9252 0.0019 0.8818 0.0111
MCF7 Fedratinib
10
uM
LJP5
0.1492 0.0020 -0.2722 0.0333
Hs 578T Gefitinib
3.33
uM
LJP6
0.9865 0.0020 0.9870 0.0020
SK-BR-3 Tozasertib
1.11
uM
LJP5
0.3462 0.0021 -0.0820 0.0584
MCF 10A Imatinib
0.37
uM
LJP6
0.9943 0.0021 0.9962 0.0017
BT-20 PD0325901
10
uM
LJP6
0.5907 0.0021 0.4529 0.0187
MCF7 XMD11-50
0.37
uM
LJP6
0.6715 0.0021 0.5992 0.0107
MCF7 XMD11-50
0.12
uM
LJP6
0.8181 0.0021 0.7843 0.0082
MCF 10A Imatinib
0.12
uM
LJP6
1.0012 0.0023 1.0009 0.0013
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