LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
Hs 578T | Canertinib | 1.11 | uM | LJP6 | 0.9427 | 0.0011 | 0.9435 | 0.0063 |
BT-20 | PD184352 | 1.11 | uM | LJP5 | 0.9888 | 0.0012 | 0.9868 | 0.0013 |
MDA-MB-231 | AZD8330 | 1.11 | uM | LJP5 | 0.2961 | 0.0012 | 0.0698 | 0.0077 |
Hs 578T | Pelitinib | 0.04 | uM | LJP5 | 0.9926 | 0.0014 | 0.9931 | 0.0008 |
Hs 578T | Y39983 | 3.33 | uM | LJP6 | 0.6510 | 0.0014 | 0.6259 | 0.0311 |
MCF 10A | GW843682X | 10 | uM | LJP6 | 0.0642 | 0.0015 | -0.1012 | 0.0992 |
MCF 10A | PD173074 | 0.12 | uM | LJP6 | 1.0089 | 0.0015 | 1.0053 | 0.0014 |
BT-20 | PIK-93 | 10 | uM | LJP5 | 0.3561 | 0.0016 | 0.0954 | 0.0256 |
BT-20 | Seliciclib | 0.12 | uM | LJP5 | 0.9975 | 0.0017 | 0.9967 | 0.0020 |
MCF 10A | PHA-665752 | 0.12 | uM | LJP5 | 0.9713 | 0.0017 | 0.9827 | 0.0026 |
SK-BR-3 | Tozasertib | 0.04 | uM | LJP5 | 0.3153 | 0.0018 | -0.1428 | 0.0652 |
MCF 10A | CP724714 | 3.33 | uM | LJP5 | 0.9742 | 0.0018 | 0.9849 | 0.0009 |
SK-BR-3 | Tozasertib | 3.33 | uM | LJP5 | 0.3411 | 0.0018 | -0.0918 | 0.0596 |
Hs 578T | PHA-665752 | 0.12 | uM | LJP5 | 1.0022 | 0.0018 | 1.0023 | 0.0017 |
SK-BR-3 | Sirolimus | 10 | uM | LJP6 | 0.6035 | 0.0019 | 0.3530 | 0.0586 |
Hs 578T | Lapatinib | 0.12 | uM | LJP6 | 0.9750 | 0.0019 | 0.9754 | 0.0042 |
SK-BR-3 | Dasatinib | 0.12 | uM | LJP6 | 0.9252 | 0.0019 | 0.8818 | 0.0111 |
MCF7 | Fedratinib | 10 | uM | LJP5 | 0.1492 | 0.0020 | -0.2722 | 0.0333 |
Hs 578T | Gefitinib | 3.33 | uM | LJP6 | 0.9865 | 0.0020 | 0.9870 | 0.0020 |
SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 0.3462 | 0.0021 | -0.0820 | 0.0584 |
MCF 10A | Imatinib | 0.37 | uM | LJP6 | 0.9943 | 0.0021 | 0.9962 | 0.0017 |
BT-20 | PD0325901 | 10 | uM | LJP6 | 0.5907 | 0.0021 | 0.4529 | 0.0187 |
MCF7 | XMD11-50 | 0.37 | uM | LJP6 | 0.6715 | 0.0021 | 0.5992 | 0.0107 |
MCF7 | XMD11-50 | 0.12 | uM | LJP6 | 0.8181 | 0.0021 | 0.7843 | 0.0082 |
MCF 10A | Imatinib | 0.12 | uM | LJP6 | 1.0012 | 0.0023 | 1.0009 | 0.0013 |