LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 1 | I20 | 72 | hr | 1235 | 1 | 4474 | 0.0002 | -0.9784 |
| MDA-MB-231 | CP466722 | 0.37 | uM | LJP5 | 2 | I10 | 72 | hr | 1235 | 1 | 4578 | 0.0002 | -0.9769 |
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 962 | 50 | 10740 | 0.0047 | -0.5724 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 658 | 19 | 3953 | 0.0048 | -0.7460 |
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 962 | 57 | 10641 | 0.0054 | -0.5574 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 658 | 23 | 3807 | 0.0060 | -0.7341 |
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 962 | 64 | 10693 | 0.0060 | -0.5416 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 658 | 24 | 3908 | 0.0061 | -0.7243 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 658 | 32 | 3938 | 0.0081 | -0.6901 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 2 | G01 | 72 | hr | 962 | 89 | 10507 | 0.0085 | -0.4985 |
| Hs 578T | PHA-665752 | 10 | uM | LJP5 | 1 | F13 | 72 | hr | 658 | 37 | 3908 | 0.0095 | -0.6737 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 658 | 41 | 3769 | 0.0109 | -0.6680 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 658 | 41 | 3705 | 0.0111 | -0.6716 |
| MCF 10A | WZ3105 | 10 | uM | LJP5 | 3 | D19 | 72 | hr | 962 | 134 | 10315 | 0.0130 | -0.4379 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 962 | 141 | 10714 | 0.0132 | -0.4244 |
| MCF 10A | A443654 | 10 | uM | LJP6 | 3 | I19 | 72 | hr | 962 | 140 | 10641 | 0.0132 | -0.4265 |
| MCF 10A | A443654 | 10 | uM | LJP6 | 1 | I19 | 72 | hr | 962 | 165 | 10693 | 0.0154 | -0.3980 |
| Hs 578T | PHA-665752 | 10 | uM | LJP5 | 3 | F13 | 72 | hr | 658 | 62 | 3938 | 0.0157 | -0.5996 |
| Hs 578T | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 658 | 62 | 3953 | 0.0157 | -0.5988 |
| MCF 10A | WZ3105 | 10 | uM | LJP5 | 1 | D19 | 72 | hr | 962 | 171 | 10714 | 0.0160 | -0.3915 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1401 | 73 | 4545 | 0.0161 | -0.8246 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 962 | 175 | 10641 | 0.0164 | -0.3883 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1235 | 75 | 4578 | 0.0164 | -0.7731 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 962 | 176 | 10641 | 0.0165 | -0.3873 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1209 | 68 | 4093 | 0.0166 | -0.8053 |