LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 1 | I20 | 72 | hr | 1235 | 1 | 4474 | 0.0002 | -0.9784 |
| MDA-MB-231 | CP466722 | 0.37 | uM | LJP5 | 2 | I10 | 72 | hr | 1235 | 1 | 4578 | 0.0002 | -0.9769 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1401 | 80 | 3978 | 0.0201 | -0.8508 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1401 | 94 | 4095 | 0.0230 | -0.8256 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1401 | 73 | 4545 | 0.0161 | -0.8246 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1401 | 94 | 4139 | 0.0227 | -0.8226 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1209 | 69 | 3823 | 0.0180 | -0.8218 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1209 | 68 | 4093 | 0.0166 | -0.8053 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1209 | 73 | 4121 | 0.0177 | -0.7956 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1401 | 122 | 4213 | 0.0290 | -0.7851 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1209 | 90 | 3980 | 0.0226 | -0.7796 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1209 | 78 | 4252 | 0.0183 | -0.7794 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1235 | 75 | 4578 | 0.0164 | -0.7731 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1401 | 139 | 4272 | 0.0325 | -0.7624 |
| MDA-MB-231 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1235 | 98 | 4277 | 0.0229 | -0.7571 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 96 | 4474 | 0.0215 | -0.7476 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 102 | 4355 | 0.0234 | -0.7466 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 658 | 19 | 3953 | 0.0048 | -0.7460 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1209 | 101 | 4376 | 0.0231 | -0.7377 |
| BT-20 | AZD8055 | 10 | uM | LJP6 | 2 | A07 | 72 | hr | 1097 | 105 | 3713 | 0.0283 | -0.7366 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 658 | 23 | 3807 | 0.0060 | -0.7341 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4929 | 0.0179 | -0.7339 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 104 | 4583 | 0.0227 | -0.7299 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 120 | 4277 | 0.0281 | -0.7280 |
| MDA-MB-231 | AT-7519 | 10 | uM | LJP6 | 2 | K01 | 72 | hr | 1235 | 122 | 4277 | 0.0285 | -0.7255 |