LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1209 | 4217 | 3980 | 1.0595 | 1.0684 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 2 | J06 | 72 | hr | 1209 | 4768 | 4252 | 1.1211 | 1.1301 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1209 | 4350 | 4376 | 0.9940 | 0.9936 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 1209 | 4156 | 3980 | 1.0442 | 1.0510 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 2 | J05 | 72 | hr | 1209 | 4246 | 4252 | 0.9984 | 0.9982 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1209 | 4167 | 4376 | 0.9522 | 0.9479 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 1209 | 3793 | 3980 | 0.9530 | 0.9447 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 2 | J04 | 72 | hr | 1209 | 3832 | 4252 | 0.9011 | 0.8884 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 1209 | 4170 | 4376 | 0.9529 | 0.9487 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1209 | 3265 | 3980 | 0.8203 | 0.7823 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 2 | J03 | 72 | hr | 1209 | 3208 | 4252 | 0.7543 | 0.7121 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1209 | 3577 | 4376 | 0.8174 | 0.7940 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 1209 | 2963 | 3980 | 0.7445 | 0.6844 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 2 | J02 | 72 | hr | 1209 | 3003 | 4252 | 0.7061 | 0.6509 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1209 | 3083 | 4376 | 0.7045 | 0.6559 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1209 | 1119 | 3980 | 0.2812 | -0.0443 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 2 | J01 | 72 | hr | 1209 | 1273 | 4252 | 0.2993 | 0.0286 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1209 | 1277 | 4376 | 0.2918 | 0.0297 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 1209 | 1413 | 3823 | 0.3696 | 0.0982 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 2 | K06 | 72 | hr | 1209 | 1892 | 4093 | 0.4622 | 0.2896 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 1209 | 1843 | 4121 | 0.4472 | 0.2689 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 1209 | 519 | 3823 | 0.1358 | -0.3993 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 2 | K05 | 72 | hr | 1209 | 721 | 4093 | 0.1761 | -0.2548 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 3 | K05 | 72 | hr | 1209 | 719 | 4121 | 0.1745 | -0.2548 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1209 | 572 | 3823 | 0.1496 | -0.3631 |