LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1401 | 5312 | 3978 | 1.3352 | 1.4234 |
| SK-BR-3 | CP466722 | 0.04 | uM | LJP5 | 1 | I12 | 72 | hr | 1401 | 5290 | 3978 | 1.3296 | 1.4167 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1401 | 5210 | 3978 | 1.3095 | 1.3924 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 1 | G08 | 72 | hr | 1401 | 5165 | 3978 | 1.2982 | 1.3786 |
| SK-BR-3 | CP466722 | 0.37 | uM | LJP5 | 1 | I10 | 72 | hr | 1401 | 5159 | 3978 | 1.2967 | 1.3768 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 1 | M06 | 72 | hr | 1401 | 5060 | 3978 | 1.2718 | 1.3464 |
| MDA-MB-231 | PD173074 | 0.37 | uM | LJP6 | 2 | I10 | 72 | hr | 1235 | 5433 | 4277 | 1.2702 | 1.2857 |
| SK-BR-3 | CP466722 | 0.12 | uM | LJP5 | 1 | I11 | 72 | hr | 1401 | 5014 | 3978 | 1.2603 | 1.3322 |
| MDA-MB-231 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 1235 | 5367 | 4277 | 1.2547 | 1.2702 |
| SK-BR-3 | WH-4-025 | 1.11 | uM | LJP5 | 1 | O09 | 72 | hr | 1401 | 4965 | 3978 | 1.2479 | 1.3170 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1401 | 4963 | 3978 | 1.2474 | 1.3164 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 1 | L18 | 72 | hr | 1401 | 4950 | 3978 | 1.2442 | 1.3124 |
| SK-BR-3 | WH-4-025 | 0.37 | uM | LJP5 | 1 | O10 | 72 | hr | 1401 | 4931 | 3978 | 1.2394 | 1.3065 |
| SK-BR-3 | CP466722 | 1.11 | uM | LJP5 | 1 | I09 | 72 | hr | 1401 | 4870 | 3978 | 1.2241 | 1.2875 |
| MDA-MB-231 | PD173074 | 1.11 | uM | LJP6 | 2 | I09 | 72 | hr | 1235 | 5218 | 4277 | 1.2199 | 1.2347 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 1 | O12 | 72 | hr | 1401 | 4832 | 3978 | 1.2145 | 1.2756 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 1 | G06 | 72 | hr | 1401 | 4829 | 3978 | 1.2138 | 1.2747 |
| BT-20 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1097 | 4493 | 3735 | 1.2029 | 1.2204 |
| SK-BR-3 | Enzastaurin | 0.37 | uM | LJP5 | 2 | D16 | 72 | hr | 1401 | 5062 | 4213 | 1.2014 | 1.2450 |
| MDA-MB-231 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1235 | 5134 | 4277 | 1.2003 | 1.2146 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1097 | 4707 | 3925 | 1.1991 | 1.2076 |
| BT-20 | uM | LJP5 | 2 | N19 | 72 | hr | 1097 | 4649 | 3877 | 1.1989 | 1.2094 | ||
| MCF7 | XL147 | 0.04 | uM | LJP5 | 1 | G12 | 72 | hr | 1209 | 4752 | 3980 | 1.1939 | 1.2173 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1401 | 5030 | 4213 | 1.1938 | 1.2361 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 1 | E12 | 72 | hr | 1401 | 4742 | 3978 | 1.1919 | 1.2474 |