LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 3 | A12 | 72 | hr | 1209 | 1254 | 4121 | 0.3043 | 0.0206 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 3 | A08 | 72 | hr | 1209 | 997 | 4121 | 0.2419 | -0.1035 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 3 | L05 | 72 | hr | 1209 | 1733 | 4121 | 0.4205 | 0.2255 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 3 | L01 | 72 | hr | 1209 | 549 | 4121 | 0.1332 | -0.3602 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 3 | A10 | 72 | hr | 1209 | 1039 | 4121 | 0.2521 | -0.0824 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 3 | A09 | 72 | hr | 1209 | 900 | 4121 | 0.2184 | -0.1539 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 3 | L06 | 72 | hr | 1209 | 1977 | 4121 | 0.4797 | 0.3202 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1209 | 4167 | 4376 | 0.9522 | 0.9479 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 3 | L04 | 72 | hr | 1209 | 1483 | 4121 | 0.3599 | 0.1221 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1209 | 3577 | 4376 | 0.8174 | 0.7940 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1209 | 500 | 4121 | 0.1213 | -0.3932 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 3 | A11 | 72 | hr | 1209 | 1137 | 4121 | 0.2759 | -0.0344 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1209 | 4350 | 4376 | 0.9940 | 0.9936 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1209 | 3083 | 4376 | 0.7045 | 0.6559 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 3 | K04 | 72 | hr | 1209 | 634 | 4121 | 0.1538 | -0.3060 |
| MCF7 | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 1209 | 408 | 4121 | 0.0990 | -0.4591 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1209 | 1277 | 4376 | 0.2918 | 0.0297 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 1209 | 4170 | 4376 | 0.9529 | 0.9487 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 3 | K03 | 72 | hr | 1209 | 691 | 4121 | 0.1677 | -0.2714 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 1209 | 1843 | 4121 | 0.4472 | 0.2689 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 3 | L03 | 72 | hr | 1209 | 1273 | 4121 | 0.3089 | 0.0293 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1209 | 992 | 4121 | 0.2407 | -0.1061 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 3 | K05 | 72 | hr | 1209 | 719 | 4121 | 0.1745 | -0.2548 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 1209 | 3898 | 4121 | 0.9458 | 0.9380 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 1209 | 409 | 4121 | 0.0992 | -0.4583 |