LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset - HMS LINCS Database

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Small molecules	Cells

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	LJP Library Plate	Replicate	Assay Well	Timepoint	Timepoint Unit	Total Cell Count Before Treatment	Total Cell Count After Treatment	Total Control Cell Count	Relative Cell Count	Normalized Growth Rate Inhibition Value
BT-20	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1097	2887	3610	0.7996	0.7559
BT-20	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1097	3198	3877	0.8247	0.7992
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1235	4089	4583	0.8921	0.8829
MDA-MB-231	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1235	1375	4929	0.2790	0.0549
BT-20	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1097	2869	3696	0.7762	0.7307
BT-20	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1097	2687	3735	0.7194	0.6599
SK-BR-3	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1401	3678	4545	0.8091	0.7653
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1235	3689	4277	0.8625	0.8414
SK-BR-3	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1401	3328	4213	0.7899	0.7239
MDA-MB-231	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1235	1288	4578	0.2813	0.0221
BT-20	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1097	2594	3713	0.6985	0.6309
MCF7	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1209	2376	4376	0.5429	0.4390
SK-BR-3	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1401	3062	4095	0.7477	0.6573
SK-BR-3	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1401	3297	4272	0.7717	0.7023
MCF7	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1209	3276	4093	0.8002	0.7620
MCF7	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1209	2044	3980	0.5136	0.3571
SK-BR-3	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1401	3393	4139	0.8198	0.7611
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1235	3343	4355	0.7675	0.7290
MCF7	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1209	3379	4121	0.8199	0.7876
SK-BR-3	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1401	2838	3978	0.7133	0.5979
MCF7	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1209	3667	3823	0.9592	0.9504
MDA-MB-231	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1235	1366	4474	0.3053	0.0554
MCF7	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1209	2145	4252	0.5044	0.3714
Hs 578T	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	658	3405	3705	0.9188	0.9332
BT-20	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1097	3250	3925	0.8279	0.8048

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HMS LINCS Project

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)