LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 962 | 11572 | 10605 | 1.0912 | 1.1003 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 962 | 11501 | 10605 | 1.0845 | 1.0930 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11451 | 10605 | 1.0798 | 1.0878 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 962 | 11416 | 10605 | 1.0765 | 1.0842 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 962 | 11413 | 10605 | 1.0762 | 1.0839 |
| MCF 10A | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 962 | 11411 | 10605 | 1.0760 | 1.0836 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 962 | 11407 | 10605 | 1.0756 | 1.0832 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 962 | 11286 | 10605 | 1.0642 | 1.0706 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 962 | 11253 | 10605 | 1.0611 | 1.0672 |
| MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 962 | 11249 | 10605 | 1.0607 | 1.0668 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 962 | 11160 | 10605 | 1.0524 | 1.0576 |
| MCF 10A | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 962 | 11123 | 10605 | 1.0489 | 1.0537 |
| MCF 10A | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11072 | 10605 | 1.0441 | 1.0485 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 962 | 11071 | 10605 | 1.0440 | 1.0484 |
| MCF 10A | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 962 | 11069 | 10605 | 1.0437 | 1.0481 |
| MCF 10A | TWS119 | 1.11 | uM | LJP5 | 72 | hr | 962 | 11066 | 10605 | 1.0435 | 1.0478 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 962 | 11066 | 10605 | 1.0435 | 1.0478 |
| MCF 10A | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 962 | 11032 | 10605 | 1.0403 | 1.0443 |
| MCF 10A | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 962 | 10963 | 10605 | 1.0338 | 1.0371 |
| MCF 10A | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 962 | 10945 | 10605 | 1.0321 | 1.0353 |
| MCF 10A | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 962 | 10944 | 10605 | 1.0320 | 1.0351 |
| MCF 10A | JW-7-24-1 | 0.04 | uM | LJP6 | 72 | hr | 962 | 10930 | 10605 | 1.0307 | 1.0338 |
| MCF 10A | A443654 | 0.04 | uM | LJP6 | 72 | hr | 962 | 10928 | 10605 | 1.0305 | 1.0336 |
| MCF 10A | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 962 | 10852 | 10605 | 1.0233 | 1.0256 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 962 | 10851 | 10605 | 1.0232 | 1.0255 |