LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4952 | 4223 | 1.1728 | 1.2586 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4944 | 4223 | 1.1707 | 1.2555 |
| SK-BR-3 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4863 | 4223 | 1.1516 | 1.2269 |
| SK-BR-3 | Nilotinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4831 | 4223 | 1.1439 | 1.2155 |
| SK-BR-3 | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4829 | 4223 | 1.1436 | 1.2150 |
| SK-BR-3 | Nilotinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4822 | 4223 | 1.1418 | 1.2123 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4821 | 4223 | 1.1417 | 1.2121 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4818 | 4223 | 1.1409 | 1.2110 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4814 | 4223 | 1.1400 | 1.2095 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4804 | 4223 | 1.1377 | 1.2061 |
| BT-20 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1097 | 4311 | 3769 | 1.1437 | 1.2027 |
| MDA-MB-231 | Enzastaurin | 10.0 | uM | LJP5 | 72 | hr | 1235 | 5177 | 4513 | 1.1470 | 1.2025 |
| BT-20 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 4302 | 3769 | 1.1413 | 1.1993 |
| BT-20 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 4280 | 3769 | 1.1356 | 1.1913 |
| BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 1097 | 4264 | 3769 | 1.1313 | 1.1852 |
| SK-BR-3 | Nilotinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4741 | 4223 | 1.1226 | 1.1836 |
| SK-BR-3 | WH-4-025 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4737 | 4223 | 1.1218 | 1.1823 |
| SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4727 | 4223 | 1.1194 | 1.1787 |
| SK-BR-3 | Nilotinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4725 | 4223 | 1.1190 | 1.1781 |
| BT-20 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1097 | 4236 | 3769 | 1.1238 | 1.1747 |
| SK-BR-3 | SB590885 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4714 | 4223 | 1.1163 | 1.1741 |
| MDA-MB-231 | PD173074 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 5078 | 4513 | 1.1252 | 1.1724 |
| MDA-MB-231 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1235 | 5069 | 4513 | 1.1232 | 1.1696 |
| Hs 578T | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 658 | 4370 | 3846 | 1.1363 | 1.1644 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4686 | 4223 | 1.1098 | 1.1643 |