DCC-2036 KiNativ -- single dose experiment - Dataset (ID:20210)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| DCC-2036 | Ramos (RA 1) | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | -13.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | -24.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | STLK5 | YSVKVLPWLSPEVLQQNLQGYDAK | Activation Loop | 5.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | -19.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | 18.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | eEF2K | YIKYNSNSGFVR | ATP | 3.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FAK2 | YIEDEDYYKASVTR | Activation Loop | 28.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | JAK1_domain2 | YDPEGDNTGEQVAVKSLKPESGGNHIADLKK | Lys1 | 19.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MLTK | WISQDKEVAVKK | Lys1 | 80.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 8.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PI4KB | VPHTQAVVLNSKDK | ATP | -10.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3CD | VNWLAHNVSKDNRQ | ATP | -3.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PKN1 | VLLSEFRPSGELFAIKALK | Lys1 | -85.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 1.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | LYN | VAVKTLKPGTMSVQAFLEEANLMK | Lys1 | 90.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AMPKa1,AMPKa2 | VAVKILNR | Lys1 | 9.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CHK2 | VAIKIISK | Lys1 | -0.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -33.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | SYK | TVAVKILK | Lys1 | -31.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FER | TSVAVKTCKEDLPQELK | Lys1 | -21.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -9.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3C3 | TEDGGKYPVIFKHGDDLR | ATP | -6.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | NEK3 | SKNIFLTQNGK | Activation Loop | 4.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | STLK6 | SIKASHILISGDGLVTLSGLSHLHSLVK | Lys2 | -1.8 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AurB | SHFIVALKVLFK | Lys1 | -84.1 | 1 | uM |