DCC-2036 KiNativ -- single dose experiment - Dataset (ID:20210)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| DCC-2036 | Ramos (RA 1) | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | >90 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -33.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AMPKa1,AMPKa2 | VAVKILNR | Lys1 | 9.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ATR | FYIMMCKPK | ATP | 21.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AurA | DIKPENLLLGSAGELK | Lys2 | -1.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AurB | SHFIVALKVLFK | Lys1 | -84.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BARK1 | DLKPANILLDEHGHVR | Lys2 | 10.8 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BRAF | DLKSNNIFLHEDLTVK | Lys2 | -17.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BTK | GQYDVAIKMIK | Lys1 | -31.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | -24.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CAMK1D | LFAVKCIPK | Lys1 | -9.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CaMK2a,CaMK2b,CaMK2d,CaMK2g | DLKPENLLLASK | Lys2 | 8.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDC2 | DLKPQNLLIDDKGTIK | Lys2 | 52.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDK11,CDK8 | DLKPANILVMGEGPER | Lys2 | 52.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDK2 | DLKPQNLLINTEGAIK | Lys2 | 61.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDK5 | DLKPQNLLINR | Lys2 | 61.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDK7 | DLKPNNLLLDENGVLK | Lys2 | -0.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CHK2 | VAIKIISK | Lys1 | -0.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | KC1A | DIKPDNFLMGIGR | Lys2 | 20.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 8.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | DNAPK | EHPFLVKGGEDLR | ATP | 34.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | eEF2K | YIKYNSNSGFVR | ATP | 3.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MK03 | DLKPSNLLINTTCDLK | Lys2 | 2.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FER | TSVAVKTCKEDLPQELK | Lys1 | -21.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 26.8 | 1 | uM |