DCC-2036 KiNativ -- single dose experiment - Dataset (ID:20210)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| DCC-2036 | Ramos (RA 1) | NEK3 | SKNIFLTQNGK | Activation Loop | 4.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | >90 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | -24.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FYN,SRC,YES | QGAKFPIKWTAPEAALYGR | Activation Loop | 39.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BLK | IIDSEYTAQEGAKFPIK | Activation Loop | 76.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | -13.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | LCK | EGAKFPIKWTAPEAINYGTFTIK | Activation Loop | 75.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FAK2 | YIEDEDYYKASVTR | Activation Loop | 28.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 8.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ZAP70 | ISDFGLSKALGADDSYYTAR | Activation Loop | 3.9 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | SYK | ISDFGLSKALR | Activation Loop | -12.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | STLK5 | YSVKVLPWLSPEVLQQNLQGYDAK | Activation Loop | 5.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 26.8 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | LYN | EGAKFPIKWTAPEAINFGCFTIK | Activation Loop | 79.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FYV1 | GGKSGAAFYATEDDRFILK | ATP | 16.9 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3CD | VNWLAHNVSKDNRQ | ATP | -3.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | DNAPK | EHPFLVKGGEDLR | ATP | 34.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | 14.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PI4KB | VPHTQAVVLNSKDK | ATP | -10.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3C3 | TEDGGKYPVIFKHGDDLR | ATP | -6.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | eEF2K | YIKYNSNSGFVR | ATP | 3.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | ATR | FYIMMCKPK | ATP | 21.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | FRAP1 | IQSIAPSLQVITSKQRPR | ATP | -15.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 1.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -9.5 | 1 | uM |