DCC-2036 KiNativ -- single dose experiment - Dataset (ID:20210)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| DCC-2036 | Ramos (RA 1) | CHK2 | VAIKIISK | Lys1 | -0.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MAP2K1,MAP2K2 | DVKPSNILVNSR | Lys2 | 0.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | NEK9 | DIKTLNIFLTK | Lys2 | 0.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | CDK7 | DLKPNNLLLDENGVLK | Lys2 | -0.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MP2K7 | DVKPSNILLDER | Lys2 | -0.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | IKKE | SGELVAVKVFNTTSYLRPR | Lys1 | -0.9 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MST2 | ESGQVVAIKQVPVESDLQEIIK | Lys1 | 0.9 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MAP2K3 | DVKPSNVLINK | Lys2 | -10.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PI4KB | VPHTQAVVLNSKDK | ATP | -10.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | JNK1,JNK2,JNK3 | DLKPSNIVVK | Lys2 | 10.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | BARK1 | DLKPANILLDEHGHVR | Lys2 | 10.8 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MARK3 | EVAIKIIDKTQLNPTSLQK | Lys1 | -11.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | MAP2K1 | IMHRDVKPSNILVNSR | Lys2 | -11.8 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | AurA | DIKPENLLLGSAGELK | Lys2 | -1.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIK3CB | VFGEDSVGVIFKNGDDLR | ATP | 1.2 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | SYK | ISDFGLSKALR | Activation Loop | -12.1 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | NDR1 | DTGHVYAMKILR | Lys1 | -12.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | SGK3 | FYAVKVLQK | Lys1 | -12.6 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | KHS1 | NVHTGELAAVKIIK | Lys1 | -13.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | NEK6,NEK7 | DIKPANVFITATGVVK | Lys2 | 13.0 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PKD3 | NIVHCDLKPENVLLASAEPFPQVK | Lys2 | 13.5 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | -13.7 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PLK1 | CFEISDADTKEVFAGKIVPK | Lys1 | -14.3 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | 14.4 | 1 | uM |
| DCC-2036 | Ramos (RA 1) | PKR | DLKPSNIFLVDTK | Lys2 | -14.7 | 1 | uM |