PCI-32765 KiNativ -- single dose experiment - Dataset (ID:20206)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | Ramos (RA 1) | NEK7 | AACLLDGVPVALKK | Lys1 | -54.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | 0.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | PLK1 | CFEISDADTKEVFAGKIVPK | Lys1 | 21.1 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MST3 | DIKAANVLLSEHGEVK | Lys2 | 12.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MST4,YSK1 | DIKAANVLLSEQGDVK | Lys2 | -8.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | TAO1,TAOK3 | DIKAGNILLTEPGQVK | Lys2 | -15.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAP3K4 | DIKGANIFLTSSGLIK | Lys2 | 22.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | M3K2,MAP3K3 | DIKGANILR | Lys2 | 21.1 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | GCK | DIKGANLLLTLQGDVK | Lys2 | -5.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAP3K5 | DIKGDNVLINTYSGVLK | Lys2 | -9.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | -45.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | NEK6,NEK7 | DIKPANVFITATGVVK | Lys2 | 14.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KC1A | DIKPDNFLMGIGR | Lys2 | -61.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | NDR2 | DIKPDNLLLDAK | Lys2 | 8.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | AurA | DIKPENLLLGSAGELK | Lys2 | 14.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | IKKE,TBK1 | DIKPGNIMR | Lys2 | -66.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | LKB1 | DIKPGNLLLTTGGTLK | Lys2 | -6.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | GSK3B | DIKPQNLLLDPDTAVLK | Lys2 | 8.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | GSK3A | DIKPQNLLVDPDTAVLK | Lys2 | 0.1 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MAP2K4 | DIKPSNILLDR | Lys2 | 7.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | IRAK4 | DIKSANILLDEAFTAK | Lys2 | 5.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | NEK9 | DIKTLNIFLTK | Lys2 | 6.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | HPK1 | DKVSGDLVALKMVK | Lys1 | -39.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MARK2,MARK3 | DLKAENLLLDADMNIK | Lys2 | -28.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | SLK | DLKAGNILFTLDGDIK | Lys2 | -4.1 | 1 | uM |