PCI-32765 KiNativ -- single dose experiment - Dataset (ID:20206)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | Ramos (RA 1) | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | -12.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -39.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | AMPKa1,AMPKa2 | VAVKILNR | Lys1 | 8.3 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | ATR | FYIMMCKPK | ATP | -76.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | AurA | DIKPENLLLGSAGELK | Lys2 | 14.5 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | AurB | SHFIVALKVLFK | Lys1 | -6.0 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BARK1 | DLKPANILLDEHGHVR | Lys2 | -1.0 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BRAF | DLKSNNIFLHEDLTVK | Lys2 | 31.0 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BTK | GQYDVAIKMIK | Lys1 | >97 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | BTK | YVLDDEYTSSVGSKFPVR | Activation Loop | 98.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CAMK1D | LFAVKCIPK | Lys1 | -20.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CaMK2a,CaMK2b,CaMK2d,CaMK2g | DLKPENLLLASK | Lys2 | -8.8 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CDC2 | DLKPQNLLIDDKGTIK | Lys2 | 16.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CDK11,CDK8 | DLKPANILVMGEGPER | Lys2 | -51.4 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CDK2 | DLKPQNLLINTEGAIK | Lys2 | -1.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CDK5 | DLKPQNLLINR | Lys2 | -2.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CDK7 | DLKPNNLLLDENGVLK | Lys2 | 7.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CHK2 | VAIKIISK | Lys1 | -1.2 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | KC1A | DIKPDNFLMGIGR | Lys2 | -61.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | CSK | VSDFGLTKEASSTQDTGKLPVK | Activation Loop | 25.6 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | DNAPK | EHPFLVKGGEDLR | ATP | -20.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | eEF2K | YIKYNSNSGFVR | ATP | -28.9 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | MK03 | DLKPSNLLINTTCDLK | Lys2 | -35.7 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | FER | TSVAVKTCKEDLPQELK | Lys1 | -16.3 | 1 | uM |
| Ibrutinib | Ramos (RA 1) | FGR | LIKDDEYNPCQGSKFPIK | Activation Loop | 54.8 | 1 | uM |