JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JWE-035 | HeLa | TEC | YVLDDQYTSSSGAkFPVK | Activation Loop | 12.1 | 10 | uM |
| JWE-035 | PC-3 | TLK2 | YVAVkIHQLNK | Lys1 | 12.7 | 10 | uM |
| JWE-035 | HeLa | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | 75.6 | 10 | uM |
| JWE-035 | HeLa | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -10.4 | 10 | uM |
| JWE-035 | PC-3 | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -1.1 | 10 | uM |
| JWE-035 | HeLa | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -9.9 | 10 | uM |
| JWE-035 | PC-3 | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -13.3 | 10 | uM |
| JWE-035 | HeLa | WEE1 | YIHSMSLVHMDIkPSNIFISR | Lys2 | 14.5 | 10 | uM |
| JWE-035 | HeLa | JAK1_domain2 | YDPEGDNTGEQVAVkSLKPESGGNHIADLKK | Lys1 | 14.8 | 10 | uM |
| JWE-035 | HeLa | TLK1 | YAAVkIHQLNK | Lys1 | -48.4 | 10 | uM |
| JWE-035 | PC-3 | TLK1 | YAAVkIHQLNK | Lys1 | 37.8 | 10 | uM |
| JWE-035 | HeLa | ILK | WQGNDIVVkVLK | Lys1 | 0.3 | 10 | uM |
| JWE-035 | PC-3 | ILK | WQGNDIVVkVLK | Lys1 | 3.0 | 10 | uM |
| JWE-035 | HeLa | MLTK | WISQDKEVAVKk | Lys1 | -5.5 | 10 | uM |
| JWE-035 | PC-3 | MLTK | WISQDKEVAVKk | Lys1 | 12.5 | 10 | uM |
| JWE-035 | PC-3 | M3K2 | VYLCYDVDTGRELAVkQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | 55.9 | 10 | uM |
| JWE-035 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -6.1 | 10 | uM |
| JWE-035 | HeLa | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 3.2 | 10 | uM |
| JWE-035 | HeLa | PI4KB | VPHTQAVVLNSkDK | ATP | -25.0 | 10 | uM |
| JWE-035 | PC-3 | PI4KB | VPHTQAVVLNSkDK | ATP | 31.7 | 10 | uM |
| JWE-035 | HeLa | PAN3 | VMDPTkILITGK | 5.8 | 10 | uM | |
| JWE-035 | HeLa | RSKL1_domain1 | VLGVIDkVLLVMDTR | Protein Kinase Domain | -401.7 | 10 | uM |
| JWE-035 | HeLa | MSK1,MSK2_domain1 | VLGTGAYGkVFLVR | ATP Loop | 4.1 | 10 | uM |
| JWE-035 | HeLa | RSK1,RSK4 domain1 | VLGQGSFGkVFLVR | ATP Loop | 9.4 | 10 | uM |
| JWE-035 | PC-3 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 1.4 | 10 | uM |