JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JWE-035 | PC-3 | MK03 | DLkPSNLLINTTCDLK | Lys2 | 2.9 | 10 | uM |
| JWE-035 | PC-3 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 41.6 | 10 | uM |
| JWE-035 | PC-3 | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -13.3 | 10 | uM |
| JWE-035 | PC-3 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 1.4 | 10 | uM |
| JWE-035 | PC-3 | FER | TSVAVkTCKEDLPQELK | Lys1 | -8.1 | 10 | uM |
| JWE-035 | PC-3 | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | 75.7 | 10 | uM |
| JWE-035 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -6.1 | 10 | uM |
| JWE-035 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 4.9 | 10 | uM |
| JWE-035 | PC-3 | EGFR | IPVAIkELR | Lys1 | 7.8 | 10 | uM |
| JWE-035 | PC-3 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | 57.2 | 10 | uM |
| JWE-035 | PC-3 | AGK | ATVFLNPAACkGK | ATP | -18.2 | 10 | uM |
| JWE-035 | PC-3 | FAK | CIGEGQFGDVHQGIYMSPENPALAVAIkTCK | Lys1 | 34.0 | 10 | uM |
| JWE-035 | PC-3 | CaMK2g | TSTQEYAAkIINTK | Lys1 | 21.0 | 10 | uM |
| JWE-035 | PC-3 | CASK | ETGQQFAVkIVDVAK | Lys1 | 16.0 | 10 | uM |
| JWE-035 | PC-3 | CDK10 | DLkVSNLLMTDK | Lys2 | 12.9 | 10 | uM |
| JWE-035 | PC-3 | CDK11,CDK8 | DLkPANILVMGEGPER | Lys2 | 0.7 | 10 | uM |
| JWE-035 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 66.4 | 10 | uM |
| JWE-035 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | 14.8 | 10 | uM |
| JWE-035 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | 34.0 | 10 | uM |
| JWE-035 | PC-3 | ATR | FYIMMCkPK | ATP | 3.6 | 10 | uM |
| JWE-035 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | 4.2 | 10 | uM |
| JWE-035 | PC-3 | CHK2 | VAIkIISK | Lys1 | 42.7 | 10 | uM |
| JWE-035 | PC-3 | KC1A | DIkPDNFLMGIGR | Lys2 | -0.4 | 10 | uM |
| JWE-035 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | -1.7 | 10 | uM |
| JWE-035 | PC-3 | GCN2_domain2 | DLkPVNIFLDSDDHVK | Lys2 | 7.1 | 10 | uM |