Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin1 | 2 | 72 | 0.001 | 6509.0 | 7167.9 | 2409.0 | -3.0 | 0.881 | 0.908 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 1 | 72 | 10.0 | 1865.0 | 7580.8 | 2503.8 | 1.0 | -0.168 | 0.246 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 10.0 | 1950.0 | 7580.8 | 2503.8 | 1.0 | -0.145 | 0.257 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 10.0 | 1998.0 | 7580.8 | 2503.8 | 1.0 | -0.132 | 0.264 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 10.0 | 1960.0 | 7580.8 | 2503.8 | 1.0 | -0.142 | 0.259 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2686.0 | 7580.8 | 2503.8 | 0.5 | 0.045 | 0.354 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2663.0 | 7580.8 | 2503.8 | 0.5 | 0.039 | 0.351 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2555.0 | 7580.8 | 2503.8 | 0.5 | 0.013 | 0.337 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 3.1623 | 2863.0 | 7580.8 | 2503.8 | 0.5 | 0.088 | 0.378 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 1772.0 | 7580.8 | 2503.8 | 0.0 | -0.195 | 0.234 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 3401.0 | 7580.8 | 2503.8 | 0.0 | 0.211 | 0.449 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 2938.0 | 7580.8 | 2503.8 | 0.0 | 0.105 | 0.388 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 1.0 | 2997.0 | 7580.8 | 2503.8 | 0.0 | 0.119 | 0.395 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.3162 | 3469.0 | 7580.8 | 2503.8 | -0.5 | 0.226 | 0.458 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.3162 | 3716.0 | 7580.8 | 2503.8 | -0.5 | 0.280 | 0.490 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.3162 | 3455.0 | 7580.8 | 2503.8 | -0.5 | 0.223 | 0.456 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.3162 | 3437.0 | 7580.8 | 2503.8 | -0.5 | 0.219 | 0.453 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4169.0 | 7580.8 | 2503.8 | -1.0 | 0.376 | 0.550 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4442.0 | 7580.8 | 2503.8 | -1.0 | 0.431 | 0.586 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 3858.0 | 7580.8 | 2503.8 | -1.0 | 0.311 | 0.509 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4134.0 | 7580.8 | 2503.8 | -1.0 | 0.369 | 0.545 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5704.0 | 7580.8 | 2503.8 | -1.5 | 0.674 | 0.752 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 4961.0 | 7580.8 | 2503.8 | -1.5 | 0.534 | 0.654 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5512.0 | 7580.8 | 2503.8 | -1.5 | 0.638 | 0.727 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5070.0 | 7580.8 | 2503.8 | -1.5 | 0.555 | 0.669 | 1.598 | HCC70 Torin1 0 1 |