Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 1 | 72 | 1.0 | 314.0 | 7580.8 | 2503.8 | 0.0 | -0.727 | 0.041 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 268.0 | 7580.8 | 2503.8 | 0.0 | -0.753 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 263.0 | 7580.8 | 2503.8 | 0.0 | -0.756 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 265.0 | 7580.8 | 2503.8 | 0.0 | -0.755 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1002.0 | 7580.8 | 2503.8 | -0.5 | -0.436 | 0.132 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1092.0 | 7580.8 | 2503.8 | -0.5 | -0.405 | 0.144 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 848.0 | 7580.8 | 2503.8 | -0.5 | -0.492 | 0.112 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 901.0 | 7580.8 | 2503.8 | -0.5 | -0.472 | 0.119 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2732.0 | 7580.8 | 2503.8 | -1.0 | 0.056 | 0.360 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2576.0 | 7580.8 | 2503.8 | -1.0 | 0.018 | 0.340 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2487.0 | 7580.8 | 2503.8 | -1.0 | -0.004 | 0.328 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2596.0 | 7580.8 | 2503.8 | -1.0 | 0.023 | 0.342 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3993.0 | 7580.8 | 2503.8 | -1.5 | 0.339 | 0.527 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3496.0 | 7580.8 | 2503.8 | -1.5 | 0.232 | 0.461 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3810.0 | 7580.8 | 2503.8 | -1.5 | 0.300 | 0.503 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3519.0 | 7580.8 | 2503.8 | -1.5 | 0.237 | 0.464 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5237.0 | 7580.8 | 2503.8 | -2.0 | 0.587 | 0.691 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 4789.0 | 7580.8 | 2503.8 | -2.0 | 0.500 | 0.632 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 4697.0 | 7580.8 | 2503.8 | -2.0 | 0.482 | 0.620 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.01 | 5027.0 | 7580.8 | 2503.8 | -2.0 | 0.547 | 0.663 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6137.0 | 7580.8 | 2503.8 | -2.49 | 0.752 | 0.810 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5842.0 | 7580.8 | 2503.8 | -2.49 | 0.699 | 0.771 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 5966.0 | 7580.8 | 2503.8 | -2.49 | 0.722 | 0.787 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0032 | 6216.0 | 7580.8 | 2503.8 | -2.49 | 0.766 | 0.820 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.001 | 6435.0 | 7580.8 | 2503.8 | -3.0 | 0.805 | 0.849 | 1.598 | HCC70 Torin2 0 1 |