Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3171.0 | 7580.8 | 2503.8 | 0.0 | 0.159 | 0.418 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4761.0 | 7580.8 | 2503.8 | -1.5 | 0.495 | 0.628 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 2978.0 | 7580.8 | 2503.8 | 0.0 | 0.115 | 0.393 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1630.0 | 7580.8 | 2503.8 | 0.0 | -0.236 | 0.215 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3414.0 | 7580.8 | 2503.8 | 0.0 | 0.214 | 0.450 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 5090.0 | 7580.8 | 2503.8 | -1.5 | 0.559 | 0.671 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3152.0 | 7580.8 | 2503.8 | 0.5 | 0.155 | 0.416 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 561.0 | 7580.8 | 2503.8 | 0.5 | -0.608 | 0.074 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3106.0 | 7580.8 | 2503.8 | 0.5 | 0.144 | 0.410 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 5257.0 | 7580.8 | 2503.8 | -1.5 | 0.591 | 0.693 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3326.0 | 7580.8 | 2503.8 | 0.5 | 0.194 | 0.439 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 10.0 | 366.0 | 7580.8 | 2503.8 | 1.0 | -0.700 | 0.048 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4744.0 | 7580.8 | 2503.8 | -1.5 | 0.492 | 0.626 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2787.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.368 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7489.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2579.0 | 7580.8 | 2503.8 | 1.0 | 0.019 | 0.340 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 4013.0 | 7580.8 | 2503.8 | -1.0 | 0.343 | 0.529 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2885.0 | 7580.8 | 2503.8 | 1.0 | 0.093 | 0.381 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 6984.0 | 7580.8 | 2503.8 | -2.49 | 0.900 | 0.921 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2785.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.367 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5715.0 | 7580.8 | 2503.8 | -2.0 | 0.676 | 0.754 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 4152.0 | 7580.8 | 2503.8 | -1.0 | 0.372 | 0.548 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 7243.0 | 7580.8 | 2503.8 | -3.0 | 0.944 | 0.955 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.001 | 6680.0 | 7580.8 | 2503.8 | -3.0 | 0.848 | 0.881 | 1.598 | HCC70 QL-V-107 0 1 |