Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 2978.0 | 7580.8 | 2503.8 | 0.0 | 0.115 | 0.393 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3414.0 | 7580.8 | 2503.8 | 0.0 | 0.214 | 0.450 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3152.0 | 7580.8 | 2503.8 | 0.5 | 0.155 | 0.416 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3106.0 | 7580.8 | 2503.8 | 0.5 | 0.144 | 0.410 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3326.0 | 7580.8 | 2503.8 | 0.5 | 0.194 | 0.439 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2787.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.368 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2579.0 | 7580.8 | 2503.8 | 1.0 | 0.019 | 0.340 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2885.0 | 7580.8 | 2503.8 | 1.0 | 0.093 | 0.381 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2785.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.367 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 4152.0 | 7580.8 | 2503.8 | -1.0 | 0.372 | 0.548 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 3940.0 | 7580.8 | 2503.8 | -1.0 | 0.328 | 0.520 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.001 | 7324.0 | 7580.8 | 2503.8 | -3.0 | 0.957 | 0.966 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.1 | 3826.0 | 7580.8 | 2503.8 | -1.0 | 0.304 | 0.505 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5758.0 | 7580.8 | 2503.8 | -2.0 | 0.684 | 0.760 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3495.0 | 7580.8 | 2503.8 | -0.5 | 0.232 | 0.461 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7489.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3684.0 | 7580.8 | 2503.8 | -0.5 | 0.273 | 0.486 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 6315.0 | 7580.8 | 2503.8 | -2.0 | 0.784 | 0.833 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3336.0 | 7580.8 | 2503.8 | -0.5 | 0.197 | 0.440 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 6984.0 | 7580.8 | 2503.8 | -2.49 | 0.900 | 0.921 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.3162 | 3363.0 | 7580.8 | 2503.8 | -0.5 | 0.203 | 0.444 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.01 | 5637.0 | 7580.8 | 2503.8 | -2.0 | 0.662 | 0.744 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 5947.0 | 7580.8 | 2503.8 | -1.5 | 0.718 | 0.784 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 5803.0 | 7580.8 | 2503.8 | -1.5 | 0.692 | 0.765 | 1.598 | HCC70 QL-IV-100 0 1 |