Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 1 | 72 | 10.0 | 555.0 | 7580.8 | 2503.8 | 1.0 | -0.610 | 0.073 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4909.0 | 7580.8 | 2503.8 | -1.0 | 0.524 | 0.648 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 5099.0 | 7580.8 | 2503.8 | -1.0 | 0.561 | 0.673 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.0316 | 7509.0 | 7580.8 | 2503.8 | -1.5 | 0.988 | 0.991 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4657.0 | 7580.8 | 2503.8 | -1.0 | 0.474 | 0.614 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 3.1623 | 3011.0 | 7580.8 | 2503.8 | 0.5 | 0.122 | 0.397 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3727.0 | 7580.8 | 2503.8 | -0.5 | 0.283 | 0.492 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 0.1 | 6000.0 | 7580.8 | 2503.8 | -1.0 | 0.728 | 0.791 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3706.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 0.0316 | 4744.0 | 7580.8 | 2503.8 | -1.5 | 0.492 | 0.626 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3705.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7422.0 | 7580.8 | 2503.8 | -3.0 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3920.0 | 7580.8 | 2503.8 | -0.5 | 0.324 | 0.517 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2787.0 | 7580.8 | 2503.8 | 1.0 | 0.069 | 0.368 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1611.0 | 7580.8 | 2503.8 | 0.0 | -0.241 | 0.213 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 8045.0 | 7580.8 | 2503.8 | -2.0 | 1.080 | 1.060 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1630.0 | 7580.8 | 2503.8 | 0.0 | -0.236 | 0.215 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 7651.0 | 7580.8 | 2503.8 | -2.0 | 1.010 | 1.010 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1549.0 | 7580.8 | 2503.8 | 0.0 | -0.260 | 0.204 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0316 | 6587.0 | 7580.8 | 2503.8 | -1.5 | 0.832 | 0.869 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1415.0 | 7580.8 | 2503.8 | 0.0 | -0.300 | 0.187 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 10.0 | 2579.0 | 7580.8 | 2503.8 | 1.0 | 0.019 | 0.340 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 642.0 | 7580.8 | 2503.8 | 0.5 | -0.573 | 0.085 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6554.0 | 7580.8 | 2503.8 | -0.5 | 0.826 | 0.865 | 1.598 | HCC70 QL-XII-108 0 1 |
| HCC70 | QL-XII-108 | 1 | 72 | 0.3162 | 6333.0 | 7580.8 | 2503.8 | -0.5 | 0.787 | 0.835 | 1.598 | HCC70 QL-XII-108 0 1 |