Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 2978.0 | 7580.8 | 2503.8 | 0.0 | 0.115 | 0.393 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3414.0 | 7580.8 | 2503.8 | 0.0 | 0.214 | 0.450 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2987.0 | 7167.9 | 2409.0 | 0.0 | 0.146 | 0.417 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1302.0 | 6533.6 | 1943.1 | 0.0 | -0.205 | 0.199 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1205.0 | 6533.6 | 1943.1 | 0.0 | -0.239 | 0.184 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2637.0 | 6533.6 | 1943.1 | 0.0 | 0.191 | 0.404 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2573.0 | 7167.9 | 2409.0 | 0.0 | 0.043 | 0.359 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 1 | 72 | 1.0 | 3289.0 | 7580.8 | 2503.8 | 0.0 | 0.186 | 0.434 | 1.598 | HCC70 AZD8055 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1415.0 | 7580.8 | 2503.8 | 0.0 | -0.300 | 0.187 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2573.0 | 6533.6 | 1943.1 | 0.0 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1562.0 | 7580.8 | 2503.8 | 0.0 | -0.256 | 0.206 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2950.0 | 6533.6 | 1943.1 | 0.0 | 0.270 | 0.452 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1353.0 | 7167.9 | 2409.0 | 0.0 | -0.307 | 0.189 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1630.0 | 7580.8 | 2503.8 | 0.0 | -0.236 | 0.215 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2886.0 | 7167.9 | 2409.0 | 0.0 | 0.122 | 0.403 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1208.0 | 7167.9 | 2409.0 | 0.0 | -0.355 | 0.169 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1363.0 | 6533.6 | 1943.1 | 0.0 | -0.183 | 0.209 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1201.0 | 7167.9 | 2409.0 | 0.0 | -0.358 | 0.168 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 3000.0 | 7167.9 | 2409.0 | 0.0 | 0.150 | 0.419 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1399.0 | 7167.9 | 2409.0 | 0.0 | -0.292 | 0.195 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 1.0 | 1333.0 | 7167.9 | 2409.0 | 0.0 | -0.314 | 0.186 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 3 | 72 | 1.0 | 2541.0 | 6533.6 | 1943.1 | 0.0 | 0.166 | 0.389 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 3 | 72 | 1.0 | 1027.0 | 6533.6 | 1943.1 | 0.0 | -0.305 | 0.157 | 1.750 | HCC70 QL-IV-100 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 3111.0 | 7580.8 | 2503.8 | 0.0 | 0.146 | 0.410 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 1.0 | 3207.0 | 7580.8 | 2503.8 | 0.0 | 0.168 | 0.423 | 1.598 | HCC70 QL-VI-86 0 1 |