Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1353.0 | 7167.9 | 2409.0 | 0.0 | -0.307 | 0.189 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1347.0 | 7167.9 | 2409.0 | 0.0 | -0.309 | 0.188 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1439.0 | 7167.9 | 2409.0 | 0.0 | -0.279 | 0.201 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1342.0 | 7167.9 | 2409.0 | 0.0 | -0.311 | 0.187 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC1806 | QL-IV-100 | 3 | 72 | 1.0 | 1846.0 | 14413.7 | 2222.1 | 0.0 | -0.066 | 0.128 | 2.697 | HCC1806 QL-IV-100 0 3 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1360.0 | 7580.8 | 2503.8 | 0.0 | -0.317 | 0.179 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-XII-47 | 3 | 72 | 1.0 | 2447.0 | 6533.6 | 1943.1 | 0.0 | 0.141 | 0.375 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC1806 | QL-V-107 | 1 | 72 | 1.0 | 6403.0 | 17793.8 | 2895.7 | 0.0 | 0.354 | 0.360 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC1806 | QL-V-107 | 1 | 72 | 1.0 | 6094.0 | 17793.8 | 2895.7 | 0.0 | 0.329 | 0.342 | 2.619 | HCC1806 QL-V-107 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 7533.0 | 7580.8 | 2503.8 | -0.5 | 0.992 | 0.994 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 6567.0 | 7580.8 | 2503.8 | -0.5 | 0.828 | 0.866 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 6070.0 | 7580.8 | 2503.8 | -0.5 | 0.740 | 0.801 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 6600.0 | 7580.8 | 2503.8 | -0.5 | 0.834 | 0.871 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 8542.0 | 17793.8 | 2895.7 | -0.5 | 0.511 | 0.480 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 6357.0 | 7580.8 | 2503.8 | -0.5 | 0.791 | 0.839 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.3162 | 7053.0 | 7580.8 | 2503.8 | -0.5 | 0.912 | 0.930 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 8860.0 | 17793.8 | 2895.7 | -0.5 | 0.533 | 0.498 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 9388.0 | 17793.8 | 2895.7 | -0.5 | 0.567 | 0.528 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.3162 | 4170.0 | 7580.8 | 2503.8 | -0.5 | 0.376 | 0.550 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.3162 | 3377.0 | 7580.8 | 2503.8 | -0.5 | 0.206 | 0.445 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 2968.0 | 7167.9 | 2409.0 | -0.5 | 0.142 | 0.414 | 1.573 | HCC70 AZD8055 0 2 |
| HCC1806 | AZD8055 | 1 | 72 | 0.3162 | 8697.0 | 17793.8 | 2895.7 | -0.5 | 0.522 | 0.489 | 2.619 | HCC1806 AZD8055 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.3162 | 3605.0 | 7580.8 | 2503.8 | -0.5 | 0.256 | 0.476 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 0.3162 | 3536.0 | 7580.8 | 2503.8 | -0.5 | 0.241 | 0.466 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 3917.0 | 6533.6 | 1943.1 | -0.5 | 0.493 | 0.600 | 1.750 | HCC70 QL-VI-86 0 3 |