Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1363.0 | 6533.6 | 1943.1 | 0.0 | -0.183 | 0.209 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 7700.0 | 7167.9 | 2409.0 | 0.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC1806 | QL-X-138 | 3 | 72 | 1.0 | 12395.0 | 14413.7 | 2222.1 | 0.0 | 0.891 | 0.860 | 2.697 | HCC1806 QL-X-138 0 3 |
| HCC70 | QL-XII-61 | 2 | 72 | 1.0 | 6916.0 | 7167.9 | 2409.0 | 0.0 | 0.955 | 0.965 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 5223.0 | 6533.6 | 1943.1 | 0.0 | 0.760 | 0.799 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 15014.0 | 17793.8 | 2895.7 | 0.0 | 0.874 | 0.844 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC70 | QL-V-107 | 3 | 72 | 1.0 | 1358.0 | 6533.6 | 1943.1 | 0.0 | -0.185 | 0.208 | 1.750 | HCC70 QL-V-107 0 3 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 4761.0 | 7167.9 | 2409.0 | 0.0 | 0.542 | 0.664 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-XII-108 | 1 | 72 | 1.0 | 15881.0 | 17793.8 | 2895.7 | 0.0 | 0.915 | 0.893 | 2.619 | HCC1806 QL-XII-108 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 4902.0 | 7167.9 | 2409.0 | 0.0 | 0.571 | 0.684 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 5897.0 | 7167.9 | 2409.0 | 0.0 | 0.767 | 0.823 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 1.0 | 5252.0 | 7167.9 | 2409.0 | 0.0 | 0.641 | 0.733 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 1.0 | 16398.0 | 18525.7 | 2822.7 | 0.0 | 0.912 | 0.885 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 1.0 | 6560.0 | 6533.6 | 1943.1 | 0.0 | 1.000 | 1.000 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1886.0 | 7580.8 | 2503.8 | 0.0 | -0.162 | 0.249 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1650.0 | 7580.8 | 2503.8 | 0.0 | -0.230 | 0.218 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1562.0 | 7580.8 | 2503.8 | 0.0 | -0.256 | 0.206 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | QL-V-107 | 1 | 72 | 1.0 | 1615.0 | 7580.8 | 2503.8 | 0.0 | -0.240 | 0.213 | 1.598 | HCC70 QL-V-107 0 1 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 3000.0 | 7167.9 | 2409.0 | 0.0 | 0.150 | 0.419 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 1.0 | 6702.0 | 6533.6 | 1943.1 | 0.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 1.0 | 5697.0 | 6533.6 | 1943.1 | 0.0 | 0.849 | 0.872 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 1.0 | 2886.0 | 7167.9 | 2409.0 | 0.0 | 0.122 | 0.403 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-X-138 | 3 | 72 | 1.0 | 4766.0 | 6533.6 | 1943.1 | 0.0 | 0.670 | 0.729 | 1.750 | HCC70 QL-X-138 0 3 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 18471.0 | 17793.8 | 2895.7 | 0.0 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 17589.0 | 17793.8 | 2895.7 | 0.0 | 0.991 | 0.988 | 2.619 | HCC1806 QL-XII-61 0 1 |