Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 2 | 72 | 10.0 | 2628.0 | 7167.9 | 2409.0 | 1.0 | 0.057 | 0.367 | 1.573 | HCC70 QL-XII-61 0 2 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.1 | 6414.0 | 6533.6 | 1943.1 | -1.0 | 0.979 | 0.982 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6297.0 | 6533.6 | 1943.1 | -3.0 | 0.958 | 0.964 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 5976.0 | 6533.6 | 1943.1 | -3.0 | 0.901 | 0.915 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6843.0 | 6533.6 | 1943.1 | -3.0 | 1.050 | 1.050 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.001 | 6699.0 | 6533.6 | 1943.1 | -3.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 6311.0 | 6533.6 | 1943.1 | -2.49 | 0.961 | 0.966 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 6055.0 | 6533.6 | 1943.1 | -2.49 | 0.915 | 0.927 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 5979.0 | 6533.6 | 1943.1 | -2.49 | 0.901 | 0.915 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0032 | 6912.0 | 6533.6 | 1943.1 | -2.49 | 1.070 | 1.060 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.01 | 6397.0 | 6533.6 | 1943.1 | -2.0 | 0.976 | 0.979 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.01 | 6456.0 | 6533.6 | 1943.1 | -2.0 | 0.986 | 0.988 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.01 | 6561.0 | 6533.6 | 1943.1 | -2.0 | 1.000 | 1.000 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.01 | 6921.0 | 6533.6 | 1943.1 | -2.0 | 1.070 | 1.060 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0316 | 5592.0 | 6533.6 | 1943.1 | -1.5 | 0.830 | 0.856 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0316 | 6701.0 | 6533.6 | 1943.1 | -1.5 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0316 | 6302.0 | 6533.6 | 1943.1 | -1.5 | 0.959 | 0.965 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.0316 | 5425.0 | 6533.6 | 1943.1 | -1.5 | 0.798 | 0.830 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.1 | 6435.0 | 6533.6 | 1943.1 | -1.0 | 0.983 | 0.985 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.1 | 6579.0 | 6533.6 | 1943.1 | -1.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.1 | 5685.0 | 6533.6 | 1943.1 | -1.0 | 0.847 | 0.870 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.3162 | 6533.0 | 6533.6 | 1943.1 | -0.5 | 1.000 | 1.000 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.3162 | 6746.0 | 6533.6 | 1943.1 | -0.5 | 1.040 | 1.030 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.3162 | 6213.0 | 6533.6 | 1943.1 | -0.5 | 0.943 | 0.951 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 0.3162 | 6690.0 | 6533.6 | 1943.1 | -0.5 | 1.030 | 1.020 | 1.750 | HCC70 QL-XII-61 0 3 |