Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VI-86 | 3 | 72 | 0.3162 | 12492.0 | 14413.7 | 2222.1 | -0.5 | 0.897 | 0.867 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.3162 | 11462.0 | 14413.7 | 2222.1 | -0.5 | 0.837 | 0.795 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VI-86 | 3 | 72 | 0.3162 | 13086.0 | 14413.7 | 2222.1 | -0.5 | 0.930 | 0.908 | 2.697 | HCC1806 QL-VI-86 0 3 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.1 | 14005.0 | 17793.8 | 2895.7 | -1.0 | 0.825 | 0.787 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0316 | 16758.0 | 17793.8 | 2895.7 | -1.5 | 0.955 | 0.942 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.1 | 13613.0 | 17793.8 | 2895.7 | -1.0 | 0.806 | 0.765 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0316 | 17349.0 | 17793.8 | 2895.7 | -1.5 | 0.981 | 0.975 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0316 | 16449.0 | 17793.8 | 2895.7 | -1.5 | 0.941 | 0.924 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0316 | 16510.0 | 17793.8 | 2895.7 | -1.5 | 0.944 | 0.928 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.1 | 14073.0 | 17793.8 | 2895.7 | -1.0 | 0.829 | 0.791 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.01 | 17293.0 | 17793.8 | 2895.7 | -2.0 | 0.978 | 0.972 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.01 | 17282.0 | 17793.8 | 2895.7 | -2.0 | 0.978 | 0.971 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.01 | 18287.0 | 17793.8 | 2895.7 | -2.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.01 | 18086.0 | 17793.8 | 2895.7 | -2.0 | 1.010 | 1.020 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.1 | 13079.0 | 17793.8 | 2895.7 | -1.0 | 0.778 | 0.735 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0032 | 18790.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0032 | 16904.0 | 17793.8 | 2895.7 | -2.49 | 0.961 | 0.950 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0032 | 18934.0 | 17793.8 | 2895.7 | -2.49 | 1.050 | 1.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.0032 | 18246.0 | 17793.8 | 2895.7 | -2.49 | 1.020 | 1.030 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 18115.0 | 17793.8 | 2895.7 | -3.0 | 1.010 | 1.020 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 17785.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 17862.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.001 | 17648.0 | 17793.8 | 2895.7 | -3.0 | 0.994 | 0.992 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.3162 | 10630.0 | 17793.8 | 2895.7 | -0.5 | 0.643 | 0.597 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 0.3162 | 10208.0 | 17793.8 | 2895.7 | -0.5 | 0.618 | 0.574 | 2.619 | HCC1806 QL-VIII-58 0 1 |