Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
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HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 16634.0 | 17793.8 | 2895.7 | -2.49 | 0.949 | 0.935 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.001 | 17216.0 | 17793.8 | 2895.7 | -3.0 | 0.975 | 0.968 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16973.0 | 17793.8 | 2895.7 | -3.0 | 0.964 | 0.954 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.0032 | 18684.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.001 | 16309.0 | 17793.8 | 2895.7 | -3.0 | 0.935 | 0.917 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.01 | 15910.0 | 17793.8 | 2895.7 | -2.0 | 0.916 | 0.894 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.0316 | 14300.0 | 17793.8 | 2895.7 | -1.5 | 0.840 | 0.804 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.0316 | 14970.0 | 17793.8 | 2895.7 | -1.5 | 0.872 | 0.841 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.0316 | 14443.0 | 17793.8 | 2895.7 | -1.5 | 0.847 | 0.812 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 1 | 72 | 0.1 | 10549.0 | 17793.8 | 2895.7 | -1.0 | 0.638 | 0.593 | 2.619 | HCC1806 AZD8055 0 1 |
HCC1806 | AZD8055 | 2 | 72 | 0.01 | 17722.0 | 18525.7 | 2822.7 | -2.0 | 0.968 | 0.957 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.01 | 17226.0 | 18525.7 | 2822.7 | -2.0 | 0.947 | 0.930 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.01 | 18160.0 | 18525.7 | 2822.7 | -2.0 | 0.985 | 0.980 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18039.0 | 18525.7 | 2822.7 | -2.49 | 0.980 | 0.974 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 11898.0 | 18525.7 | 2822.7 | -2.49 | 0.699 | 0.642 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18863.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.020 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.01 | 16856.0 | 18525.7 | 2822.7 | -2.0 | 0.932 | 0.910 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.001 | 17923.0 | 18525.7 | 2822.7 | -3.0 | 0.976 | 0.967 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.001 | 18510.0 | 18525.7 | 2822.7 | -3.0 | 0.999 | 0.999 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.001 | 18239.0 | 18525.7 | 2822.7 | -3.0 | 0.989 | 0.985 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.001 | 18210.0 | 18525.7 | 2822.7 | -3.0 | 0.987 | 0.983 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0032 | 18499.0 | 18525.7 | 2822.7 | -2.49 | 0.999 | 0.999 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15946.0 | 18525.7 | 2822.7 | -1.5 | 0.893 | 0.861 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15293.0 | 18525.7 | 2822.7 | -1.5 | 0.864 | 0.826 | 2.714 | HCC1806 AZD8055 0 2 |
HCC1806 | AZD8055 | 2 | 72 | 0.0316 | 15618.0 | 18525.7 | 2822.7 | -1.5 | 0.878 | 0.843 | 2.714 | HCC1806 AZD8055 0 2 |