Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-V-107 | 2 | 72 | 1.0 | 6710.0 | 18525.7 | 2822.7 | 0.0 | 0.376 | 0.362 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 1.0 | 6418.0 | 18525.7 | 2822.7 | 0.0 | 0.353 | 0.346 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 3.1623 | 1850.0 | 18525.7 | 2822.7 | 0.5 | -0.144 | 0.100 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.3162 | 11744.0 | 18525.7 | 2822.7 | -0.5 | 0.691 | 0.634 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.1 | 15502.0 | 18525.7 | 2822.7 | -1.0 | 0.873 | 0.837 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.3162 | 11578.0 | 18525.7 | 2822.7 | -0.5 | 0.682 | 0.625 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.1 | 13977.0 | 18525.7 | 2822.7 | -1.0 | 0.803 | 0.754 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 16978.0 | 18525.7 | 2822.7 | -1.5 | 0.937 | 0.916 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17594.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17934.0 | 18525.7 | 2822.7 | -1.5 | 0.976 | 0.968 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.01 | 18451.0 | 18525.7 | 2822.7 | -2.0 | 0.997 | 0.996 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 2 | 72 | 0.0316 | 17828.0 | 18525.7 | 2822.7 | -1.5 | 0.972 | 0.962 | 2.714 | HCC1806 QL-V-107 0 2 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 14351.0 | 14413.7 | 2222.1 | -2.49 | 0.997 | 0.996 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 15287.0 | 14413.7 | 2222.1 | -2.0 | 1.040 | 1.060 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 14825.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 14213.0 | 14413.7 | 2222.1 | -2.0 | 0.990 | 0.986 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 6411.0 | 14413.7 | 2222.1 | -2.49 | 0.481 | 0.445 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 13568.0 | 14413.7 | 2222.1 | -2.49 | 0.956 | 0.941 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0032 | 14218.0 | 14413.7 | 2222.1 | -2.49 | 0.990 | 0.986 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.001 | 14579.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.001 | 13343.0 | 14413.7 | 2222.1 | -3.0 | 0.944 | 0.926 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.001 | 13599.0 | 14413.7 | 2222.1 | -3.0 | 0.957 | 0.943 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.001 | 14631.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.0316 | 13418.0 | 14413.7 | 2222.1 | -1.5 | 0.948 | 0.931 | 2.697 | HCC1806 QL-V-107 0 3 |
| HCC1806 | QL-V-107 | 3 | 72 | 0.01 | 14847.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-V-107 0 3 |