Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 QL-V-107 1 72
0.3162
 11128.0 17793.8 2895.7
-0.5
 0.672 0.625 2.619
HCC1806 QL-V-107 0 1
HCC1806 QL-V-107 2 72
0.1
 16534.0 18525.7 2822.7
-1.0
 0.918 0.892 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.1
 14846.0 18525.7 2822.7
-1.0
 0.843 0.801 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.1
 15502.0 18525.7 2822.7
-1.0
 0.873 0.837 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17828.0 18525.7 2822.7
-1.5
 0.972 0.962 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17934.0 18525.7 2822.7
-1.5
 0.976 0.968 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.1
 13977.0 18525.7 2822.7
-1.0
 0.803 0.754 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.3162
 11744.0 18525.7 2822.7
-0.5
 0.691 0.634 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.01
 18451.0 18525.7 2822.7
-2.0
 0.997 0.996 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.01
 18494.0 18525.7 2822.7
-2.0
 0.999 0.998 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 17594.0 18525.7 2822.7
-1.5
 0.962 0.950 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0032
 17887.0 18525.7 2822.7
-2.49
 0.974 0.966 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.01
 18228.0 18525.7 2822.7
-2.0
 0.988 0.984 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.01
 19141.0 18525.7 2822.7
-2.0
 1.020 1.030 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0316
 16978.0 18525.7 2822.7
-1.5
 0.937 0.916 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.3162
 11578.0 18525.7 2822.7
-0.5
 0.682 0.625 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0032
 18450.0 18525.7 2822.7
-2.49
 0.997 0.996 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0032
 18868.0 18525.7 2822.7
-2.49
 1.010 1.020 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.001
 17964.0 18525.7 2822.7
-3.0
 0.977 0.970 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.001
 17998.0 18525.7 2822.7
-3.0
 0.979 0.972 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.001
 17620.0 18525.7 2822.7
-3.0
 0.963 0.951 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.001
 18505.0 18525.7 2822.7
-3.0
 0.999 0.999 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.0032
 18358.0 18525.7 2822.7
-2.49
 0.993 0.991 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.3162
 11225.0 18525.7 2822.7
-0.5
 0.663 0.606 2.714
HCC1806 QL-V-107 0 2
HCC1806 QL-V-107 2 72
0.3162
 12296.0 18525.7 2822.7
-0.5
 0.720 0.664 2.714
HCC1806 QL-V-107 0 2