Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6268.0 | 7167.9 | 2409.0 | -3.0 | 0.837 | 0.874 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 6850.0 | 7167.9 | 2409.0 | -2.49 | 0.943 | 0.956 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 7367.0 | 7167.9 | 2409.0 | -2.49 | 1.040 | 1.030 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 6908.0 | 7167.9 | 2409.0 | -2.49 | 0.954 | 0.964 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.01 | 5822.0 | 7167.9 | 2409.0 | -2.0 | 0.752 | 0.812 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 3917.0 | 7167.9 | 2409.0 | -1.5 | 0.362 | 0.546 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 4267.0 | 7167.9 | 2409.0 | -1.5 | 0.438 | 0.595 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3681.0 | 7167.9 | 2409.0 | -1.0 | 0.309 | 0.514 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.1 | 3427.0 | 7167.9 | 2409.0 | -1.0 | 0.251 | 0.478 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.3162 | 3078.0 | 7167.9 | 2409.0 | -0.5 | 0.169 | 0.429 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6736.0 | 7167.9 | 2409.0 | -3.0 | 0.923 | 0.940 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6624.0 | 7167.9 | 2409.0 | -3.0 | 0.902 | 0.924 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6048.0 | 7167.9 | 2409.0 | -3.0 | 0.795 | 0.844 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6775.0 | 7167.9 | 2409.0 | -3.0 | 0.930 | 0.945 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6432.0 | 7167.9 | 2409.0 | -2.49 | 0.867 | 0.897 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6349.0 | 7167.9 | 2409.0 | -2.49 | 0.852 | 0.886 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6438.0 | 7167.9 | 2409.0 | -2.49 | 0.868 | 0.898 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0032 | 6454.0 | 7167.9 | 2409.0 | -2.49 | 0.871 | 0.900 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5681.0 | 7167.9 | 2409.0 | -2.0 | 0.725 | 0.793 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5600.0 | 7167.9 | 2409.0 | -2.0 | 0.710 | 0.781 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 6054.0 | 7167.9 | 2409.0 | -2.0 | 0.796 | 0.845 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.01 | 5690.0 | 7167.9 | 2409.0 | -2.0 | 0.727 | 0.794 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.0316 | 4487.0 | 7167.9 | 2409.0 | -1.5 | 0.485 | 0.626 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0316 | 5652.0 | 7167.9 | 2409.0 | -1.5 | 0.720 | 0.789 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0316 | 4988.0 | 7167.9 | 2409.0 | -1.5 | 0.588 | 0.696 | 1.573 | HCC70 QL-IV-100 0 2 |