Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1353.0 | 7167.9 | 2409.0 | 0.0 | -0.307 | 0.189 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1347.0 | 7167.9 | 2409.0 | 0.0 | -0.309 | 0.188 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1439.0 | 7167.9 | 2409.0 | 0.0 | -0.279 | 0.201 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 1.0 | 1342.0 | 7167.9 | 2409.0 | 0.0 | -0.311 | 0.187 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 629.0 | 7167.9 | 2409.0 | 0.5 | -0.574 | 0.088 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 558.0 | 7167.9 | 2409.0 | 0.5 | -0.605 | 0.078 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 680.0 | 7167.9 | 2409.0 | 0.5 | -0.552 | 0.095 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 3.1623 | 658.0 | 7167.9 | 2409.0 | 0.5 | -0.562 | 0.092 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 10.0 | 487.0 | 7167.9 | 2409.0 | 1.0 | -0.638 | 0.068 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 10.0 | 402.0 | 7167.9 | 2409.0 | 1.0 | -0.680 | 0.056 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 10.0 | 422.0 | 7167.9 | 2409.0 | 1.0 | -0.670 | 0.059 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | QL-V-107 | 2 | 72 | 10.0 | 502.0 | 7167.9 | 2409.0 | 1.0 | -0.631 | 0.070 | 1.573 | HCC70 QL-V-107 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 10.0 | 2141.0 | 7167.9 | 2409.0 | 1.0 | -0.072 | 0.299 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6750.0 | 7167.9 | 2409.0 | -3.0 | 0.925 | 0.942 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 0.3162 | 4456.0 | 7167.9 | 2409.0 | -0.5 | 0.478 | 0.622 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6268.0 | 7167.9 | 2409.0 | -3.0 | 0.837 | 0.874 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 1.0 | 2427.0 | 7167.9 | 2409.0 | 0.0 | 0.005 | 0.339 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6210.0 | 7167.9 | 2409.0 | -3.0 | 0.826 | 0.866 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 3.1623 | 841.0 | 7167.9 | 2409.0 | 0.5 | -0.488 | 0.117 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6454.0 | 7167.9 | 2409.0 | -3.0 | 0.871 | 0.900 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 0.001 | 6736.0 | 7167.9 | 2409.0 | -3.0 | 0.923 | 0.940 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 6850.0 | 7167.9 | 2409.0 | -2.49 | 0.943 | 0.956 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-VI-86 | 2 | 72 | 10.0 | 337.0 | 7167.9 | 2409.0 | 1.0 | -0.714 | 0.047 | 1.573 | HCC70 QL-VI-86 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.01 | 7238.0 | 7167.9 | 2409.0 | -2.0 | 1.010 | 1.010 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 0.01 | 7165.0 | 7167.9 | 2409.0 | -2.0 | 0.999 | 1.000 | 1.573 | HCC70 QL-XII-47 0 2 |