Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-X-138 | 1 | 72 | 3.1623 | 12925.0 | 17793.8 | 2895.7 | 0.5 | 0.770 | 0.726 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-X-138 | 1 | 72 | 3.1623 | 13387.0 | 17793.8 | 2895.7 | 0.5 | 0.794 | 0.752 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-X-138 | 1 | 72 | 3.1623 | 13292.0 | 17793.8 | 2895.7 | 0.5 | 0.789 | 0.747 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC1806 | QL-X-138 | 1 | 72 | 3.1623 | 12762.0 | 17793.8 | 2895.7 | 0.5 | 0.762 | 0.717 | 2.619 | HCC1806 QL-X-138 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 27.0 | 7167.9 | 2409.0 | 0.5 | -0.942 | 0.004 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 48.0 | 7167.9 | 2409.0 | 0.5 | -0.917 | 0.007 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 43.0 | 7167.9 | 2409.0 | 0.5 | -0.923 | 0.006 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 59.0 | 7167.9 | 2409.0 | 0.5 | -0.905 | 0.008 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 7193.0 | 18525.7 | 2822.7 | 0.5 | 0.411 | 0.388 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 6542.0 | 18525.7 | 2822.7 | 0.5 | 0.363 | 0.353 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 6598.0 | 18525.7 | 2822.7 | 0.5 | 0.367 | 0.356 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 5883.0 | 18525.7 | 2822.7 | 0.5 | 0.311 | 0.318 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 3.1623 | 4671.0 | 14413.7 | 2222.1 | 0.5 | 0.317 | 0.324 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2590.0 | 7167.9 | 2409.0 | 0.5 | 0.047 | 0.361 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2848.0 | 7167.9 | 2409.0 | 0.5 | 0.112 | 0.397 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2831.0 | 7167.9 | 2409.0 | 0.5 | 0.108 | 0.395 | 1.573 | HCC70 AZD8055 0 2 |
| HCC70 | AZD8055 | 2 | 72 | 3.1623 | 2838.0 | 7167.9 | 2409.0 | 0.5 | 0.110 | 0.396 | 1.573 | HCC70 AZD8055 0 2 |
| HCC1806 | QL-V-73 | 3 | 72 | 3.1623 | 3859.0 | 14413.7 | 2222.1 | 0.5 | 0.227 | 0.268 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-V-73 | 3 | 72 | 3.1623 | 4172.0 | 14413.7 | 2222.1 | 0.5 | 0.263 | 0.289 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-V-73 | 3 | 72 | 3.1623 | 4743.0 | 14413.7 | 2222.1 | 0.5 | 0.325 | 0.329 | 2.697 | HCC1806 QL-V-73 0 3 |
| HCC1806 | QL-X-138 | 2 | 72 | 3.1623 | 13936.0 | 18525.7 | 2822.7 | 0.5 | 0.801 | 0.752 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 2 | 72 | 3.1623 | 12959.0 | 18525.7 | 2822.7 | 0.5 | 0.753 | 0.700 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 2 | 72 | 3.1623 | 13473.0 | 18525.7 | 2822.7 | 0.5 | 0.779 | 0.727 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC1806 | QL-X-138 | 2 | 72 | 3.1623 | 13258.0 | 18525.7 | 2822.7 | 0.5 | 0.768 | 0.716 | 2.714 | HCC1806 QL-X-138 0 2 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 61.0 | 7580.8 | 2503.8 | 0.5 | -0.902 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |